食用坚果对认知功能的影响：一项随机临床试验的系统评价和荟萃分析
The effect of consuming nuts on cognitive function: a systematic review and meta-analysis of randomized clinical trials.
作者信息
Moabedi Mahdi, Aliakbari Mohammadreza, Erfanian Shima, Jibril Aliyu Tijani, Milajerdi Alireza
机构信息
Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Front Nutr. 2024 Sep 4;11:1463801. doi: 10.3389/fnut.2024.1463801. eCollection 2024.
BACKGROUND
Results from clinical trials investigating the effect of nuts consumption on cognition are conflicting. We decided to conduct the current meta-analysis to summarize all available evidence on the effect of consuming nuts on cognition scores.
METHODS
We conducted a comprehensive search in the online databases using relevant keywords up to June 2024. We included all the published Randomized clinical trials (RCTs) investigating the effect of nuts, compared to control, on cognition scores.
RESULTS
Overall, 5 trials were included with a total sample size of 928 adults. Based on 6 effect sizes from these 5 trials, we did not find a significant effect of nuts on cognition function [Standardized Mean Difference (SMD): 0.27, 95% CI: -0.65 to 1.19, = 0.57].
CONCLUSION
Our review could not find a significant effect of nuts on cognition function. Future high-quality RCTs with larger sample sizes should be conducted to shed light on the impact of nuts on cognition.
背景
关于食用坚果对认知影响的临床试验结果相互矛盾。我们决定进行当前的荟萃分析，以总结有关食用坚果对认知得分影响的所有现有证据。
方法
截至2024年6月，我们使用相关关键词在在线数据库中进行了全面搜索。我们纳入了所有已发表的随机临床试验（RCT），这些试验研究了与对照组相比，坚果对认知得分的影响。
结果
总体而言，纳入了5项试验，总样本量为928名成年人。基于这5项试验的6个效应量，我们未发现坚果对认知功能有显著影响[标准化均值差（SMD）：0.27，95%置信区间：-0.65至1.19，P = 0.57]。
结论
我们的综述未发现坚果对认知功能有显著影响。未来应开展样本量更大的高质量RCT，以阐明坚果对认知的影响。
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