Unit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.
Operative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Nutrients. 2021 Oct 18;13(10):3646. doi: 10.3390/nu13103646.
Vestibular disorders may generate complex signs and symptoms, which may alter patients' balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and relations. Despite the presence of conventional drugs, maneuvers, and surgery, another interesting therapeutic opportunity is offered by nutraceuticals. These molecules are often used in the treatment of dizziness and vertigo, but the rationale of their application is not always solidly demonstrated by the scientific evidence. Several substances have shown a variable level of efficacy/usefulness in this field, but there is lack of important evidence for most of them. From a medico-legal point of view, specific information must be provided to the patient regarding the efficacy and possibilities that the use of these preparations can allow. Administering the right nutraceutical to the proper patient is a fundamental clinical skill. Integrating conventional drug treatment with nutraceutical administration seems to be easy, but it may be difficult considering the (in part unexplored) pharmacodynamics and pharmacokinetics of nutraceuticals. The aim of the scientific community should be to elevate nutraceuticals to the same law and technical dignity of conventional drugs.
前庭障碍可能产生复杂的症状和体征,这些症状和体征可能会改变患者的平衡和生活质量。头晕和眩晕会强烈影响日常活动和人际关系。尽管有常规药物、手法和手术,但营养疗法提供了另一种有趣的治疗机会。这些分子常用于治疗头晕和眩晕,但它们应用的基本原理并不总是被科学证据充分证明。在这一领域,有几种物质表现出不同程度的疗效/有用性,但其中大多数缺乏重要证据。从医学法律的角度来看,必须向患者提供有关这些制剂疗效和使用可能性的具体信息。为合适的患者提供正确的营养疗法是一项基本的临床技能。将常规药物治疗与营养疗法结合似乎很简单,但考虑到营养疗法的(部分未被探索的)药效学和药代动力学,这可能很困难。科学界的目标应该是将营养疗法提升到与传统药物相同的法律和技术地位。