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新型纳米羟基磷灰石-二氧化硅添加型玻璃离子水门汀与天然牙齿之间特定元素的离子交换分析

Analysis of Ionic-Exchange of Selected Elements between Novel Nano-Hydroxyapatite-Silica Added Glass Ionomer Cement and Natural Teeth.

作者信息

Moheet Imran Alam, Luddin Norhayati, Ab Rahman Ismail, Masudi Sam'an Malik, Kannan Thirumulu Ponnuraj, Nik Abd Ghani Nik Rozainah

机构信息

Baqai Dental College, Baqai Medical University, Karachi 75340, Pakistan.

School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.

出版信息

Polymers (Basel). 2021 Oct 12;13(20):3504. doi: 10.3390/polym13203504.

DOI:10.3390/polym13203504
PMID:34685263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8537145/
Abstract

One of the foremost missions in restorative dentistry is to discover a suitable material that can substitute lost and damaged tooth structure. To this date, most of the restorative materials utilized in dentistry are bio-inert. It is predicted that the addition of nano-HA-SiO to GIC matrix could produce a material with better ion-exchange between the restorative material and natural teeth. Therefore, the aim of the current study was to synthesize and investigate the transfer of specific elements (calcium, phosphorus, fluoride, silica, strontium, and alumina) between nano-hydroxyapatite-silica added GIC (nano-HA-SiO-GIC) and human enamel and dentine. The novel nano-hydroxyapatite-silica (nano-HA-SiO) was synthesized using one-pot sol-gel method and added to cGIC. Semi-quantitative energy dispersive X-ray (EDX) analysis was carried out to determine the elemental distribution of fluorine, silicon, phosphorus, calcium, strontium, and aluminum. Semi-quantitative energy dispersive X-ray (EDX) analysis was performed by collecting line-scans and dot-scans. The results of the current study seem to confirm the ionic exchange between nano-HA-SiO-GIC and natural teeth, leading to the conclusion that increased remineralization may be possible with nano-HA-SiO-GIC as compared to cGIC (Fuji IX).

摘要

口腔修复学的首要任务之一是找到一种合适的材料来替代缺失和受损的牙齿结构。迄今为止，牙科中使用的大多数修复材料都是生物惰性的。据预测，向玻璃离子水门汀（GIC）基质中添加纳米羟基磷灰石-二氧化硅（nano-HA-SiO）可以产生一种在修复材料与天然牙齿之间具有更好离子交换性能的材料。因此，本研究的目的是合成并研究添加了纳米羟基磷灰石-二氧化硅的GIC（nano-HA-SiO-GIC）与人类牙釉质和牙本质之间特定元素（钙、磷、氟、硅、锶和铝）的转移情况。采用一锅溶胶-凝胶法合成了新型纳米羟基磷灰石-二氧化硅（nano-HA-SiO）并添加到传统GIC（cGIC）中。进行了半定量能量色散X射线（EDX）分析，以确定氟、硅、磷、钙、锶和铝的元素分布。通过收集线扫描和点扫描进行半定量能量色散X射线（EDX）分析。本研究结果似乎证实了nano-HA-SiO-GIC与天然牙齿之间的离子交换，得出的结论是，与cGIC（富士IX）相比，nano-HA-SiO-GIC可能具有更强的再矿化能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/d80d25c8ebe4/polymers-13-03504-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/795bcc70b79c/polymers-13-03504-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/153070d40496/polymers-13-03504-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/8c0973b99e1d/polymers-13-03504-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/fad7889e06dd/polymers-13-03504-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/61c22ed21787/polymers-13-03504-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/d80d25c8ebe4/polymers-13-03504-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/795bcc70b79c/polymers-13-03504-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/153070d40496/polymers-13-03504-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/8c0973b99e1d/polymers-13-03504-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/fad7889e06dd/polymers-13-03504-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/61c22ed21787/polymers-13-03504-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbc/8537145/d80d25c8ebe4/polymers-13-03504-g006.jpg

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