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首次鉴定到的轮状病毒的分子特征。

Molecular Characterization of the First Alternavirus Identified in .

机构信息

College of Plant Protection, Henan Agricultural University, Zhengzhou 450002, China.

State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.

出版信息

Viruses. 2021 Oct 8;13(10):2026. doi: 10.3390/v13102026.

DOI:10.3390/v13102026
PMID:34696456
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8538667/
Abstract

A novel mycovirus named Fusarium oxysporum alternavirus 1(FoAV1) was identified as infecting strain BH19, which was isolated from a fusarium wilt diseased stem of . The genome of FoAV1 contains four double-stranded RNA (dsRNA) segments (dsRNA1, dsRNA 2, dsRNA 3 and dsRNA 4, with lengths of 3.3, 2.6, 2.3 and 1.8 kbp, respectively). Additionally, dsRNA1 encodes RNA-dependent RNA polymerase (RdRp), and dsRNA2- dsRNA3- and dsRNA4-encoded hypothetical proteins (ORF2, ORF3 and ORF4), respectively. A homology BLAST search, along with multiple alignments based on RdRp, ORF2 and ORF3 sequences, identified FoAV1 as a novel member of the proposed family ". Evolutionary relation analyses indicated that FoAV1 may be related to alternaviruses, thus dividing the family " members into four clades. In addition, we determined that dsRNA4 was dispensable for replication and may be a satellite-like RNA of FoAV1-and could perhaps play a role in the evolution of alternaviruses. Our results provided evidence for potential genera establishment within the proposed family ". Additionally, FoAV1 exhibited biological control of Fusarium wilt. Our results also laid the foundations for the further study of mycoviruses within the family ", and provide a potential agent for the biocontrol of diseases caused by .

摘要

一种名为尖孢镰刀菌交替病毒 1（FoAV1）的新型真菌病毒被鉴定为感染菌株 BH19，该菌株是从 枯萎病患病茎中分离出来的。FoAV1 的基因组包含四个双链 RNA（dsRNA）片段（dsRNA1、dsRNA2、dsRNA3 和 dsRNA4，长度分别为 3.3、2.6、2.3 和 1.8 kbp）。此外，dsRNA1 编码 RNA 依赖性 RNA 聚合酶（RdRp），dsRNA2-dsRNA3 和 dsRNA4 编码假定蛋白（ORF2、ORF3 和 ORF4）。同源性 BLAST 搜索以及基于 RdRp、ORF2 和 ORF3 序列的多重比对将 FoAV1 鉴定为拟议家族“ ”的新型成员。进化关系分析表明，FoAV1 可能与交替病毒有关，因此将家族“ ”成员分为四个分支。此外，我们确定 dsRNA4 对于复制是可有可无的，可能是 FoAV1 的卫星样 RNA，也许在交替病毒的进化中发挥作用。我们的研究结果为拟议家族内潜在属的建立提供了证据。此外，FoAV1 表现出对镰刀菌枯萎病的生物防治作用。我们的研究结果还为进一步研究家族内的真菌病毒奠定了基础，并为利用 防治疾病提供了一种潜在的生物防治剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/27e32a887233/viruses-13-02026-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/916a7f037ced/viruses-13-02026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/d8db354f1c47/viruses-13-02026-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/64f5219125fd/viruses-13-02026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/c10139cbd101/viruses-13-02026-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/36240f65c3e3/viruses-13-02026-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/d78e236a5897/viruses-13-02026-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/53b593dc4c00/viruses-13-02026-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/27e32a887233/viruses-13-02026-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/916a7f037ced/viruses-13-02026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/d8db354f1c47/viruses-13-02026-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/64f5219125fd/viruses-13-02026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/c10139cbd101/viruses-13-02026-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/36240f65c3e3/viruses-13-02026-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/d78e236a5897/viruses-13-02026-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/53b593dc4c00/viruses-13-02026-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbb3/8538667/27e32a887233/viruses-13-02026-g008.jpg

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2
Fusarium oxysporum and its biocontrol.尖孢镰刀菌及其生物防治
New Phytol. 2003 Mar;157(3):493-502. doi: 10.1046/j.1469-8137.2003.00700.x.
3
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A Novel Strain of Fusarium oxysporum Virus 1 Isolated from f. sp. Strain X-GS16 Influences Phenotypes of Strain HB-TS-YT-1.
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J Fungi (Basel). 2024 Mar 27;10(4):252. doi: 10.3390/jof10040252.
4
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5
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