虚拟现实训练对髌股关节疼痛女性临床指标及脑图谱的影响：一项随机临床试验。
The effects of virtual reality training on clinical indices and brain mapping of women with patellofemoral pain: a randomized clinical trial.
作者信息
Ebrahimi Naghmeh, Rojhani-Shirazi Zahra, Yoosefinejad Amin Kordi, Nami Mohammad
机构信息
Student Research Committee, School of Rehabilitation Sciences, Shiraz University of Medical Sciences, Chamran Blvd., Abiverdi 1Street, P.O. Box: 71345-1733, Shiraz, Iran.
Department of Physical Therapy, School of Rehabilitation Sciences, Shiraz University of Medical Sciences, Chamran Blvd., Abiverdi 1Street, P.O. Box: 71345-1733, Shiraz, Iran.
出版信息
BMC Musculoskelet Disord. 2021 Oct 25;22(1):900. doi: 10.1186/s12891-021-04785-6.
BACKGROUND
Virtual reality training (VRT) is a new method for the rehabilitation of musculoskeletal impairments. However, the clinical and central effects of VRT have not been investigated in patients with patellofemoral pain (PFP). To comprehensively assess the effects of VRT on clinical indices and brain function, we used a randomized clinical trial based on clinical and brain mapping assessment.
METHODS
Twenty-six women with PFP for more than 6 months were randomly allocated to 2 groups: intervention and control. The intervention consisted of lifestyle education + 8 weeks VRT, in 24 sessions each lasting 40 min of training, whereas the control group just received lifestyle education. The balance was the primary outcome and was measured by the modified star excursion balance test. Secondary outcomes included pain, function, quality of life, and brain function which were assessed by visual analogue scale, step down test and Kujala questionnaire, SF-36, and EEG, respectively. Pre-intervention, post-intervention and follow-up (1 month after the end of the intervention) measurements were taken for all outcome measures except EEG, which was evaluated only at pre-intervention and post-intervention). Analyses of variance was used to compare the clinical outcomes between the two groups. The independent t-test also was used for between group EEG analyses.
RESULTS
Balance score (P < 0.001), function (P < 0.001), and quality of life (P = 0.001) improved significantly at post-intervention and 1 month follow-up in the VRT group compared with the control group. VRT group showed a significantly decreased pain score (P = 0.004). Alpha (P < 0.05) and theta (P = 0.01) power activity also increased in the brain of the VRT group.
CONCLUSION
This study demonstrated that long term VRT was capable of improving both clinical impairments and brain function in patients with PFP. Therefore, therapists and clinicians can use this method as a more holistic approach in the rehabilitation of PFP.
TRIAL REGISTRATION
IRCT, IRCT20090831002391N40 . Registered 23 / 10 / 2019.
背景
虚拟现实训练（VRT）是一种用于肌肉骨骼损伤康复的新方法。然而，尚未对髌股疼痛（PFP）患者进行VRT的临床及中枢效应研究。为全面评估VRT对临床指标和脑功能的影响，我们采用了基于临床和脑图谱评估的随机临床试验。
方法
26名患有PFP超过6个月的女性被随机分为两组：干预组和对照组。干预措施包括生活方式教育 + 为期8周的VRT，共24节训练课程，每节持续40分钟，而对照组仅接受生活方式教育。平衡能力是主要结局指标，通过改良的星标偏移平衡测试进行测量。次要结局指标包括疼痛、功能、生活质量和脑功能，分别通过视觉模拟量表、下台阶测试和库贾拉问卷、SF - 36以及脑电图进行评估。除脑电图仅在干预前和干预后进行评估外，对所有结局指标在干预前、干预后及随访（干预结束后1个月）时进行测量。采用方差分析比较两组的临床结局。独立t检验也用于两组间的脑电图分析。
结果
与对照组相比，VRT组在干预后及1个月随访时平衡评分（P < 0.001）、功能（P < 0.001）和生活质量（P = 0.001）均有显著改善。VRT组的疼痛评分显著降低（P = 0.004）。VRT组大脑中的α波（P < 0.05）和θ波（P = 0.01）功率活动也有所增加。
结论
本研究表明，长期VRT能够改善PFP患者的临床损伤和脑功能。因此，治疗师和临床医生可将此方法作为PFP康复中更全面的方法。
试验注册
IRCT，IRCT20090831002391N40。于2019年10月23日注册。
Zotero 插件