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一种罕见的胸腺肿瘤——脂肪纤维腺瘤——总是术后的惊喜。

A Rare Thymic Tumor - Lipofibroadenoma - Always a Postoperative Surprise.

机构信息

Thoracic Surgery Department, "Marius Nasta" National Institute of Pneumology, Bucharest, Romania.

Faculty of Medicine and Health Sciences, Sherbrooke University, Sherbrooke, QC, Canada.

出版信息

In Vivo. 2021 Nov-Dec;35(6):3623-3626. doi: 10.21873/invivo.12668.

DOI:10.21873/invivo.12668
PMID:34697204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8627725/
Abstract

BACKGROUND/AIM: Thymic lipofibroadenoma is a benign growth of unknown etiology extremely rarely described in the literature, morphologically resembling lipofibroadenoma of the breast. The diagnosis is usually a postoperative surprise and is made by the anatomopathologist. Surgical resection is curative.

CASE REPORT

The presented case is the first reported in a woman, to date. The patient was successfully submitted to surgery and complete resection of the giant intrathoracic tumor was performed. The histopathological and immunohistochemical studies came to demonstrated the presence of a thymic lipofibroadenoma while the postoperative outcomes were favorable.

CONCLUSION

In cases presenting large intrathoracic tumors complete resection is able to provide a significant improvement of the general condition of the patient, as well as a chance for cure.

摘要

背景/目的:胸腺脂肪纤维腺瘤是一种良性肿瘤,其病因不明,在文献中极为罕见,形态上类似于乳腺的脂肪纤维腺瘤。诊断通常是术后的意外发现,由解剖病理学家做出。手术切除是可治愈的。

病例报告

本例是迄今为止首例报道的女性病例。该患者成功接受了手术,完整切除了巨大的胸腔内肿瘤。组织病理学和免疫组织化学研究证实存在胸腺脂肪纤维腺瘤,且术后结果良好。

结论

对于出现大型胸腔内肿瘤的病例,完整切除能够显著改善患者的整体状况,并提供治愈的机会。

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A Rare Thymic Tumor - Lipofibroadenoma - Always a Postoperative Surprise.一种罕见的胸腺肿瘤——脂肪纤维腺瘤——总是术后的惊喜。
In Vivo. 2021 Nov-Dec;35(6):3623-3626. doi: 10.21873/invivo.12668.
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引用本文的文献

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Thymic lipofibroadenoma: A case report.胸腺脂肪纤维腺瘤:一例报告。
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Asymptomatic lipofibroadenoma in a 17-year-old male: a case report and literature review of a rare entity.17岁男性无症状性脂肪纤维瘤:1例病例报告及罕见实体的文献综述
Mediastinum. 2022 Dec 16;7:19. doi: 10.21037/med-22-32. eCollection 2023.
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Lipofibroadenoma and other rare thymic tumors: a call for misfits.脂肪纤维腺瘤及其他罕见胸腺肿瘤:对异类的呼吁。
Mediastinum. 2023 Mar 30;7:11. doi: 10.21037/med-23-4. eCollection 2023.
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Surgical resection of a giant thymolipoma causing respiratory failure: A case report.手术切除导致呼吸衰竭的巨大胸腺脂肪瘤:一例报告。
World J Clin Cases. 2023 Feb 16;11(5):1137-1143. doi: 10.12998/wjcc.v11.i5.1137.
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Thymic lipofibroadenomas: Three case reports.胸腺脂肪纤维腺瘤:三例病例报告。
World J Clin Cases. 2023 Jan 6;11(1):164-171. doi: 10.12998/wjcc.v11.i1.164.
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Healthcare (Basel). 2022 Nov 11;10(11):2267. doi: 10.3390/healthcare10112267.
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本文引用的文献

1
Lipofibroadenoma with B1 thymoma: A case report of a rare thymic tumor.伴B1型胸腺瘤的脂肪纤维腺瘤:一例罕见胸腺肿瘤的病例报告
Indian J Pathol Microbiol. 2018 Oct-Dec;61(4):630-632. doi: 10.4103/IJPM.IJPM_443_17.
2
Successful Resection of Giant Mediastinal Lipofibroadenoma of the Thymus by Video-Assisted Thoracoscopic Surgery.电视辅助胸腔镜手术成功切除巨大胸腺纵隔脂肪纤维腺瘤
Ann Thorac Surg. 2015 Aug;100(2):698-700. doi: 10.1016/j.athoracsur.2014.09.069.
3
A rare thymoma type presenting as a giant intrathoracic tumor: lipofibroadenoma.一种表现为巨大胸内肿瘤的罕见胸腺瘤类型:脂肪纤维腺瘤。
Eurasian J Med. 2012 Dec;44(3):176-8. doi: 10.5152/eajm.2012.41.
4
Lipofibroadenoma of the thymus: a case report.胸腺脂肪纤维瘤:一例报告。
Diagn Pathol. 2013 Jul 15;8:117. doi: 10.1186/1746-1596-8-117.
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Minimally invasive surgery in cancer. Immunological response.癌症中的微创手术。免疫反应。
Chirurgia (Bucur). 2012 Mar-Apr;107(2):154-7.
6
[Lipofibroadenoma of the thymus].[胸腺脂肪纤维腺瘤]
Kyobu Geka. 2009 May;62(5):395-8.
7
Thymic epithelial tumours: a population-based study of the incidence, diagnostic procedures and therapy.胸腺上皮肿瘤:一项基于人群的发病率、诊断程序及治疗的研究。
Eur J Cancer. 2008 Jan;44(1):123-30. doi: 10.1016/j.ejca.2007.11.004.
8
Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies.美国的恶性胸腺瘤:发病率的人口统计学模式及其与后续恶性肿瘤的关联。
Int J Cancer. 2003 Jul 1;105(4):546-51. doi: 10.1002/ijc.11099.
9
Histologic types of thymoma associated with pure red cell aplasia: a study of five cases including a composite tumor of organoid thymoma associated with an unusual lipofibroadenoma.与纯红细胞再生障碍相关的胸腺瘤组织学类型:一项包括类器官胸腺瘤与罕见脂肪纤维腺瘤复合肿瘤的5例病例研究。
Int J Surg Pathol. 2001 Jan;9(1):29-35. doi: 10.1177/106689690100900106.
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Thymofibrolipoma. A histologic variant of thymolipoma.胸腺纤维脂肪瘤。胸腺脂肪瘤的一种组织学变异型。
Arch Pathol Lab Med. 1994 Mar;118(3):281-2.