胸腺脂肪纤维腺瘤：三例病例报告。

Thymic lipofibroadenomas: Three case reports.

作者信息

Yang Mai-Qing, Wang Zhi-Qiang, Chen Li-Qian, Gao Su-Mei, Fu Xing-Ning, Zhang Hai-Ning, Zhang Ke-Xin, Xu Hong-Tao

机构信息

Department of Pathology, Weifang People's Hospital (First Affiliated Hospital of Weifang Medical University), Weifang 261041, Shandong Province, China.

Department of Orthopedics and Trauma, Weifang People's Hospital (First Affiliated Hospital of Weifang Medical University), Weifang 261041, Shandong Province, China.

出版信息

World J Clin Cases. 2023 Jan 6;11(1):164-171. doi: 10.12998/wjcc.v11.i1.164.

DOI:10.12998/wjcc.v11.i1.164

PMID:36687181

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9846990/

Abstract

BACKGROUND

Thymic lipofibroadenomas are extremely rare. In this study, we investigated the clinicopathological characteristics of thymic lipofibroadenomas.

CASE SUMMARY

This study included three patients with thymic lipofibroadenomas. We retrospectively analyzed the patient data to determine the clinicopathological characteristics of thymic lipofibroadenomas. The study included one man and two women [mean age, 43 (33-59) years]. All patients were non-smokers and presented with well-defined anterior mediastinal tumors. The cut surfaces of the tumors were solid, with a mixture of yellow and white areas. Microscopic evaluation of resected specimens showed scattered cord-like structures of epithelial cells embedded within abundant fibrotic and hyaline stroma admixed with variable quantities of adipose tissue. One patient showed hyperplastic thymic tissue in a part of the tumor.

CONCLUSION

Thymic lipofibroadenomas are an extremely rare type of benign thymic tumor. Surgical removal of lipofibroadenomas is usually curative.

摘要

背景

胸腺脂肪纤维腺瘤极为罕见。在本研究中，我们调查了胸腺脂肪纤维腺瘤的临床病理特征。

病例总结

本研究纳入了3例胸腺脂肪纤维腺瘤患者。我们回顾性分析患者数据以确定胸腺脂肪纤维腺瘤的临床病理特征。该研究包括1名男性和2名女性[平均年龄43（33 - 59）岁]。所有患者均不吸烟，表现为边界清晰的前纵隔肿瘤。肿瘤切面为实性，有黄色和白色区域混合。对切除标本的显微镜评估显示，上皮细胞呈散在的条索状结构，包埋于丰富的纤维化和透明样间质中，并混有不同数量的脂肪组织。1例患者在肿瘤的一部分显示胸腺组织增生。