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对(L.)杜纳尔的批判性综述:非洲的民族植物学、药理功效及商业化意义

Critical review of the (L.) Dunal: ethnobotany, pharmacological efficacy, and commercialization significance in Africa.

作者信息

Afewerky Henok Kessete, Ayodeji Ayeni Emmanuel, Tiamiyu Bashir Bolaji, Orege Joshua Iseoluwa, Okeke Emmanuel Sunday, Oyejobi Aanuoluwapo Opeyemi, Bate Petuel Ndip Ndip, Adeyemi Sherif Babatunde

机构信息

Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 China.

Department of Pathology and Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 China.

出版信息

Bull Natl Res Cent. 2021;45(1):176. doi: 10.1186/s42269-021-00635-6. Epub 2021 Oct 21.

DOI:10.1186/s42269-021-00635-6
PMID:34697529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8529567/
Abstract

BACKGROUND

(L.) Dunal () is a herb commonly known by its English name as Winter Cherry. Africa is indigenous to many medicinal plants and natural products. However, there is inadequate documentation of medicinal plants, including , in Africa. There is, therefore, a need for a comprehensive compilation of research outcomes of this reviewed plant as used in traditional medicine in different regions of Africa.

METHODOLOGY

Scientific articles and publications were scooped and sourced from high-impact factor journals and filtered with relevant keywords on . Scientific databases, including GBIF, PubMed, NCBI, Google Scholar, Research Gate, Science Direct, SciFinder, and Web of Science, were accessed to identify the most influential articles and recent breakthroughs published on the contexts of ethnography, ethnomedicinal uses, phytochemistry, pharmacology, and commercialization of .

RESULTS

This critical review covers the ethnography, phytochemistry, and ethnomedicinal usage to demonstrate the use of the plant in Africa and elsewhere to prevent or alleviate several pathophysiological conditions, including cardiovascular, neurodegenerative, reproductive impotence, as well as other chronic diseases.

CONCLUSION

is reportedly safe for administration in ethnomedicine as several research outcomes confirmed its safety status. The significance of commercializing this plant in Africa for drug development is herein thoroughly covered to provide the much-needed highlights towards its cultivations economic benefit to Africa.

摘要

背景

酸浆(Physalis alkekengi (L.) Dunal)是一种草本植物,其英文名通常为冬珊瑚。非洲原产许多药用植物和天然产物。然而,包括酸浆在内的非洲药用植物的文献记录并不充分。因此,需要全面汇编这种经审查的植物在非洲不同地区传统医学中的研究成果。

方法

从高影响力期刊中搜集科学文章和出版物,并使用与酸浆相关的关键词进行筛选。访问了包括GBIF、PubMed、NCBI、谷歌学术、Research Gate、ScienceDirect、SciFinder和科学网在内的科学数据库,以识别在酸浆的人种志、民族药用用途、植物化学、药理学和商业化方面发表的最具影响力的文章和最新突破。

结果

这篇批判性综述涵盖了酸浆的人种志、植物化学和民族药用用途,以证明该植物在非洲和其他地方用于预防或缓解多种病理生理状况,包括心血管疾病、神经退行性疾病、生殖功能障碍以及其他慢性疾病。

结论

据报道,在民族医学中使用酸浆是安全的,因为多项研究结果证实了其安全状况。本文全面探讨了在非洲将这种植物商业化用于药物开发的意义,以突出其种植对非洲的经济效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa30/8529567/aeb30a281acf/42269_2021_635_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa30/8529567/290538513e8a/42269_2021_635_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa30/8529567/aeb30a281acf/42269_2021_635_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa30/8529567/290538513e8a/42269_2021_635_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa30/8529567/aeb30a281acf/42269_2021_635_Fig2_HTML.jpg

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