天然还原水对老年人认知功能、身体成分和心理功能的影响：一项随机对照试验的研究方案
Effects of Natural Reduced Water on Cognitive Function, Body Composition, and Psychological Function in Older Adults: Study Protocol for a Randomized Controlled Trial.
作者信息
Shinada Takamitsu, Takano Yuji, Kokubun Keisuke, Iki Hikari, Taki Yasuyuki
机构信息
Smart-Aging Research Center, Tohoku University, 4-1 Seiryo-Machi, Aoba-ku, Sendai 980-8575, Japan.
Department of Psychology, University of Human Environments, Matsuyama, Ehime 790-0825, Japan.
出版信息
Methods Protoc. 2021 Oct 14;4(4):73. doi: 10.3390/mps4040073.
Natural reduced water is natural water that contains active hydrogen and reduces oxidation. It is rare in the world, and in Japan, it is produced in the Hita area of Oita Prefecture (Hita Tenryosui water). Previous studies in humans have examined the effects of natural reduced water on diabetes, which is one of the known risks for dementia. Animal studies of natural reduced water have revealed anti-obesity and anti-anxiety effects. However, the effects of natural reduced water on cognitive function, body composition, and psychological function in humans are unknown. Therefore, we investigated the relationship between these items in elderly people who continuously consume natural reduced water. In this study, we recruited participants aged between 65 and 74 years. The participants were randomly and blindly assigned to a natural reduced water (Hita Tenryosui water) group or a control (tap water) group and drank 1 L of water daily for 6 months. Cognitive function, body composition, and psychological function were measured before and after the 6-month intervention period.
天然还原水是含有活性氢并能减少氧化的天然水。它在世界上很罕见，在日本，它产自大分县日田地区（日田天然良质水）。此前针对人类的研究考察了天然还原水对糖尿病（痴呆症已知风险之一）的影响。对天然还原水的动物研究揭示了其抗肥胖和抗焦虑作用。然而，天然还原水对人类认知功能、身体组成和心理功能的影响尚不清楚。因此，我们调查了持续饮用天然还原水的老年人中这些指标之间的关系。在本研究中，我们招募了年龄在65至74岁之间的参与者。参与者被随机、盲法分配到天然还原水（日田天然良质水）组或对照组（自来水），并连续6个月每天饮用1升水。在为期6个月的干预期前后测量认知功能、身体组成和心理功能。
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