Department of Interventional Radiology, University hospital Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.
PLoS One. 2021 Oct 26;16(10):e0259127. doi: 10.1371/journal.pone.0259127. eCollection 2021.
Port implantations at the forearm are associated with an increased risk of relevant vein thrombosis. Therefore, with this study we sought to identify the responsible risk factors to improve technical quality of the method.
This is a retrospective analysis of 313 patients with port implantation at the forearm in 2019. Then, exploratory statistics were conducted comprising Cox-Regression and Kaplan-Meier-Analyses.
Mean age was 60 ± 14 years. 232 (74%) of the patients were female. No early infection was observed. 29 late infections and 57 cases of thrombosis occurred. In only 9% of the patients with thrombosis hospital admission was necessary for treatment. Median interval to the diagnosis of thrombosis was 23 days; inter-quartile-range: 16-75. Mean interval to elective port explantation was 227 ± 128 days. There was no effect of occurrence of thrombosis of the interventionalist, the assistance nor of several technical aspects. However, there was a significantly lower risk of thrombosis for primary implanted port system compared to replacement ports, Hazard-ratio: 0.34 [Confidence interval: 0.172, 0.674], p = 0.002. Age was a significant risk factor for late infections, Hazard-ratio: 3.35 [Confidence interval:1.84, 6.07], p < 0.0001.
The main risk factor for adverse outcome after radiographically guided port implantation at the forearm is the type of the implanted port system. The reason for that might not be the material itself but the experience of a team with a certain port system. Age is a risk factor for late complications.
在前臂植入端口会增加相关静脉血栓形成的风险。因此，本研究旨在确定相关风险因素，以提高该方法的技术质量。
这是对 2019 年在前臂植入 313 例端口的患者进行的回顾性分析。然后进行了探索性统计分析，包括 Cox 回归和 Kaplan-Meier 分析。
平均年龄为 60 ± 14 岁。232 例（74%）患者为女性。未观察到早期感染。发生了 29 例晚期感染和 57 例血栓形成。只有 9%的血栓形成患者需要住院治疗。诊断血栓形成的中位间隔时间为 23 天；四分位间距：16-75。择期取出端口的平均间隔时间为 227 ± 128 天。血栓形成的发生与介入医生、助手或多个技术方面无关。然而，与更换端口相比，原发性植入端口系统发生血栓的风险显著降低，风险比：0.34[置信区间：0.172，0.674]，p = 0.002。年龄是晚期感染的一个显著危险因素，风险比：3.35[置信区间：1.84，6.07]，p < 0.0001。
经影像学引导在前臂植入端口后不良结果的主要危险因素是植入端口系统的类型。原因可能不是材料本身，而是团队使用特定端口系统的经验。年龄是晚期并发症的危险因素。
