Heidemann M K
J Exp Zool. 1978 May;204(2):249-57. doi: 10.1002/jez.1402040212.
The experiments reported here describe quantitatively wiping responses elicited from three equal body sections of adult Rana pipiens having had one of two types of skin-graft operations as tadpoles. These experiments assessed the development of aberrant wiping responses in individuals and populations of grafted animals. Grafting parameters critical for the development of aberrant wiping responses were also determined. These studies indicated that the phenomenon of "misdirected responses" and the extent of these responses is highly variable among grafted individuals and between different populations of grafted animals. In addition, the development of "misdirected responses" is independent of premetamorphic stimulation and of a critical grafting period. The proportion of "misdirected responses" elicited upon cutaneous stimulation of individuals appears to be stable and predictable after metamorphosis. "Misdirected responses" could be elicited from animals with grafts including over 40% of the trunk skin. Wiping responses and grafting parameters of skin-grafted R. pipiens in other studies are also presented and possible sources of interstudy variation discussed.
此处报告的实验定量描述了成年豹蛙（Rana pipiens）在蝌蚪期接受两种皮肤移植手术之一后，从其三个相等身体部位引发的擦拭反应。这些实验评估了移植动物个体和群体中异常擦拭反应的发展情况。还确定了对异常擦拭反应发展至关重要的移植参数。这些研究表明，“反应方向错误”现象及其反应程度在移植个体之间以及不同移植动物群体之间存在高度差异。此外，“反应方向错误”的发展与变态前刺激以及关键移植期无关。个体皮肤受到刺激时引发的“反应方向错误”比例在变态后似乎是稳定且可预测的。“反应方向错误”可从移植皮肤超过躯干皮肤40%的动物身上引发。还介绍了其他研究中皮肤移植豹蛙的擦拭反应和移植参数，并讨论了研究间差异的可能来源。
