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孕妇和哺乳期妇女对 COVID-19 疫苗接种的态度和担忧。

Pregnant and breastfeeding women's attitudes and fears regarding the COVID-19 vaccination.

机构信息

Department of Experimental Psychology, Heinrich-Heine-University Düsseldorf, Universitätsstraße 1, 40225, Düsseldorf, Germany.

Department of Obstetrics, University Hospital, Jena, Germany.

出版信息

Arch Gynecol Obstet. 2022 Aug;306(2):365-372. doi: 10.1007/s00404-021-06297-z. Epub 2021 Oct 27.

Abstract

PURPOSE

The COVID-19 vaccination is probably the most important source to fight the COVID-19 pandemic. However, recommendations and possibilities for vaccination for pregnant and breastfeeding women are inconsistent and dynamically changing.

METHODS

An anonymous, online, cross-sectional survey was conducted among pregnant and breastfeeding women in Germany between 30th March and 19th April 2021 addressing COVID-19 vaccination attitudes including the underlying reasons for their decision. Additionally, anxiety regarding a SARS-CoV-2 infection and a symptomatic course of the infection were evaluated.

RESULTS

In total, 2339 women (n = 1043 pregnant and n = 1296 breastfeeding) completed the survey. During pregnancy the majority (57.4%) are not in favour of receiving the vaccine, 28.8% are unsure and only 13.8% would get vaccinated at the time of the survey. In contrast, 47.2% would be in favour to receive the vaccine, if more scientific evidence on the safety of the vaccination during pregnancy would be available. Breastfeeding women show higher vaccination willingness (39.5% are in favour, 28.1% are unsure and 32.5% not in favour). The willingness to be vaccinated is significantly related to the women's anxiety levels of getting infected and to develop disease symptoms. Main reasons for vaccination hesitancy are the women's perception of limited vaccination-specific information, limited scientific evidence on vaccination safety and the fear to harm the fetus or infant.

CONCLUSIONS

The results provide important implications for obstetrical care during the pandemic as well as for official recommendations und information strategies regarding the COVID-19 vaccination.

摘要

目的

COVID-19 疫苗接种可能是抗击 COVID-19 大流行的最重要手段。然而,对于孕妇和哺乳期妇女的疫苗接种建议和可能性并不一致,且处于动态变化中。

方法

2021 年 3 月 30 日至 4 月 19 日期间,我们以匿名、在线、横断面的方式对德国的孕妇和哺乳期妇女进行了调查,以了解其对 COVID-19 疫苗接种的态度,包括其决定的潜在原因。此外,还评估了对 SARS-CoV-2 感染和症状性感染的焦虑程度。

结果

共有 2339 名女性(n=1043 名孕妇和 n=1296 名哺乳期妇女)完成了调查。怀孕期间,大多数(57.4%)人不赞成接种疫苗,28.8%的人不确定,只有 13.8%的人会在调查时接种疫苗。相比之下,如果有更多关于怀孕期间疫苗接种安全性的科学证据,47.2%的人会赞成接种疫苗。哺乳期妇女的疫苗接种意愿更高(39.5%赞成,28.1%不确定,32.5%不赞成)。接种疫苗的意愿与女性感染和出现疾病症状的焦虑程度显著相关。接种犹豫不决的主要原因是女性对有限的疫苗特定信息的感知、有限的疫苗接种安全性的科学证据以及对伤害胎儿或婴儿的恐惧。

结论

这些结果为大流行期间的产科护理以及 COVID-19 疫苗接种的官方建议和信息策略提供了重要启示。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2df/9349164/a4772ed19011/404_2021_6297_Fig1_HTML.jpg

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