Lee Shu Yu, Pothiawala Sohil, Meng Seet Chong
Department of Emergency Medicine, Woodlands Health Campus, National Healthcare Group, Singapore E-mail:
Department of Emergency Medicine, Sengkang General Hospital, Singhealth Services, Singapore.
Qatar Med J. 2021 Oct 7;2021(3):52. doi: 10.5339/qmj.2021.52. eCollection 2021.
Adenosine is frequently used for paroxysmal supraventricular tachycardia (PSVT) treatment in the emergency department (ED). Atrial and ventricular pro-arrhythmic effects of adenosine were described in the literature, but ventricular fibrillation (VF) secondary to adenosine administration was rarely reported (with an incidence of < 1%). Reported herein is the first case of a 72-year-old female patient who developed VF hemodynamic collapse after an intravenous administration of adenosine for PSVT treatment. She had no known pre-excitation or accessory pathway, nor any underlying structural heart disease or prolonged QT syndrome. Raising awareness of this potential life-threatening pro-arrhythmic effect of adenosine is important, given its frequent use for PSVT treatment in the ED.
腺苷常用于急诊科（ED）阵发性室上性心动过速（PSVT）的治疗。文献中描述了腺苷对心房和心室的促心律失常作用，但腺苷给药继发心室颤动（VF）的情况鲜有报道（发生率<1%）。本文报告了首例72岁女性患者，其在静脉注射腺苷治疗PSVT后发生VF血流动力学崩溃。她既往无预激或旁路，也无任何潜在的结构性心脏病或长QT综合征。鉴于腺苷在ED中常用于PSVT治疗，提高对这种潜在危及生命的促心律失常作用的认识很重要。
