Gibore Nyasiro S, Munyogwa Mariam J, Ng'weshemi Secilia K, Gesase Ainory P
School of Nursing and Public Health, The University of Dodoma, P.O. Box 395, Dodoma, Tanzania.
School of Medicine and Dentistry, The University of Dodoma, P.O. Box 395, Dodoma, Tanzania.
Biol Methods Protoc. 2021 Oct 7;6(1):bpab019. doi: 10.1093/biomethods/bpab019. eCollection 2021.
Tanzania is experiencing the rise of cardiovascular diseases (CVDs) and associated risk factors including hypertension, obesity and diabetes mellitus. Health education and healthy lifestyle promotion is an effective approach toward primary prevention of the risk factors and can be achieved through community-based intervention. The objective of this protocol is to test the effectiveness of community-based lifestyle education intervention in reducing CVDs risk factors among vulnerable population in Dodoma City. This protocol is designed as a cluster-randomized controlled trial with a quantitative approach in which participants aged from 31 years will be assigned randomly to a control or intervention group. A total of 800 participants will be recruited in the study. The study will consist of six stages (baseline, first to fourth follow-up, and end-line surveys) in 6 months for both the intervention and the control group. The intervention will be implemented twice-monthly for the first 3 months, then monthly for the last 3 months. In each stage, participants from all groups will be measured for biological and behavioral CVDs risk factors. Health education and a healthy lifestyle promotion for prevention of CVDs risk factors will be provided to the intervention group only during each stage. The main outcome measures will be changes in body weight, blood pressure, blood glucose, dietary habits, and physical exercise in the intervention compared with the control group. Independent and paired -tests will be employed to make comparisons between and within groups. -values of less than 0.05 will be considered statistically significant.
坦桑尼亚正经历心血管疾病（CVDs）以及包括高血压、肥胖症和糖尿病在内的相关风险因素的增加。健康教育和促进健康的生活方式是对这些风险因素进行一级预防的有效方法，并且可以通过基于社区的干预措施来实现。本方案的目的是测试基于社区的生活方式教育干预在降低多多马市弱势群体心血管疾病风险因素方面的有效性。本方案设计为一项采用定量方法的整群随机对照试验，其中31岁及以上的参与者将被随机分配到对照组或干预组。本研究将招募800名参与者。干预组和对照组的研究将在6个月内包括六个阶段（基线、第一次至第四次随访以及终线调查）。干预措施在前3个月每半月实施一次，后3个月每月实施一次。在每个阶段，将对所有组的参与者进行心血管疾病生物和行为风险因素的测量。仅在每个阶段向干预组提供预防心血管疾病风险因素的健康教育和促进健康的生活方式。主要结局指标将是与对照组相比，干预组体重、血压、血糖、饮食习惯和体育锻炼的变化。将采用独立样本和配对样本检验在组间和组内进行比较。p值小于0.05将被视为具有统计学意义。
