Lu Xin-Yan, Wang Fei, Zhang Li-Min, Ren Xiao-Ming, Yu Nan-Yang, Wei Si
State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China.
Jiangsu Provincial Environmental Engineering Technology Co., Ltd., Nanjing 210000, China.
Huan Jing Ke Xue. 2021 Nov 8;42(11):5284-5293. doi: 10.13227/j.hjkx.202103114.
Emerging pollutants occur in the environment, which has become a pressing issue for environmental research. In order to comprehensively screen potential polar organic pollutants in surface water of Wujin and Yixing in the Taihu Lake Basin, nontarget screening was carried out by high performance liquid chromatography(HPLC) and time of flight mass spectrometry(TOF-MS). Screened by accurate mass, isotope distribution, and MS/MS information, 162 organic compounds were identified, including 46 pesticides, 34 drugs, 8 personal care products, and 27 additives; 17 organic synthetic intermediates and 30 metabolites, 45 of which have been verified by reference standards. Through the quantitative analysis of 42 pollutants and ecological risk assessment of 3 trophic model species, it was found that 25 pollutants posed medium risk while 12 pollutants presented high risk. Nontarget screening can be used to identify potential pollutants with no prior information or standards. It is not only fast, accurate, and has high analytical flux, but also provides an important basis for subsequent ecological risk assessment.
新兴污染物在环境中出现，这已成为环境研究中的一个紧迫问题。为了全面筛查太湖流域武进和宜兴地表水潜在的极性有机污染物，采用高效液相色谱（HPLC）和飞行时间质谱（TOF-MS）进行非靶向筛查。通过精确质量、同位素分布和MS/MS信息筛选，鉴定出162种有机化合物，包括46种农药、34种药物、8种个人护理产品和27种添加剂；17种有机合成中间体和30种代谢物，其中45种已通过参考标准验证。通过对42种污染物的定量分析和对3种营养级模式物种的生态风险评估，发现25种污染物具有中等风险，12种污染物具有高风险。非靶向筛查可用于在没有先验信息或标准的情况下识别潜在污染物。它不仅快速、准确且分析通量高，还为后续生态风险评估提供重要依据。
