Simonsson T, Edwardsson S, Glantz P O
Scand J Dent Res. 1987 Feb;95(1):43-8.
In order to trace factors possibly influencing initial bacterial colonization of tooth surfaces, a multiple linear regression analysis was performed on the present results as well as on those from certain clinical and biochemical studies previously performed in the same subjects. No statistically significant differences were observed between the two groups of plaque formers for the individual parameters. The multiple regression analysis showed, however, that the calculated work of adhesion for two polar and one non polar test liquid, the rate of unstimulated salivary secretion, morphologic differences in the dento-gingival areas of maxillary premolars and saliva-induced aggregation of S. mitior were crucial for about 90% of the variation in the number of CFU colonizing tooth surfaces after both 2 and 6 h. Both electrostatic and van der Waal's forces, as well as salivary flow conditions could thus have influenced the initial attachment of bacteria to the test surfaces. It is concluded that saliva including its suspended microorganisms could be looked upon as being a colloidal biological system, and if so, the initial bacterial colonization of tooth surfaces should follow known, general biophysical laws.
为了探寻可能影响牙齿表面初始细菌定植的因素，对本研究结果以及之前在同一受试者身上进行的某些临床和生化研究结果进行了多元线性回归分析。两组菌斑形成者在各个参数上均未观察到统计学上的显著差异。然而，多元回归分析表明，两种极性和一种非极性测试液体的计算粘附功、非刺激性唾液分泌速率、上颌前磨牙牙-龈区域的形态差异以及唾液诱导的轻链球菌聚集，对于2小时和6小时后定植于牙齿表面的菌落形成单位数量约90%的变化至关重要。因此，静电力和范德华力以及唾液流动状况都可能影响细菌在测试表面的初始附着。得出的结论是，包括其悬浮微生物在内的唾液可被视为一种胶体生物系统，如果是这样，牙齿表面的初始细菌定植应遵循已知的一般生物物理规律。
