Simonsson T, Rönström A, Rundegren J, Birkhed D
Scand J Dent Res. 1987 Apr;95(2):97-103. doi: 10.1111/j.1600-0722.1987.tb01814.x.
The purpose of the present study was to give a clinical and biochemical characterization of two groups of individuals with different rates of plaque formation. From 133 individuals, 9 "heavy" and 10 "light" plaque formers were selected. The mean plaque index after 3 days of plaque accumulation, on buccal surfaces of premolars and first molars, was 2.6 for the "heavy" and 0.6 for the "light" plaque formers. The following variables were determined: periodontal status, DFS, dietary habits, salivary secretion rate and buffer effect, S. mutans and lactobacillus counts in saliva, salivary content of IgA, lactoferrin, lactoperoxidase and lysozyme, saliva-induced aggregation of certain oral streptococci, gel electrophoresis of saliva, amino acid composition of saliva and the acquired pellicle and retention depth of the dentogingival area. Comparing the two groups of plaque formers, statistically significant differences were found for the following three variables: parotid saliva-induced aggregation of a strain of S. sanguis, content of glutamic acid in the acquired pellicle and retention depth of the dentogingival area for maxillary premolars. Large variations for all studied variables were found, both within and between the groups. Several factors may be involved in plaque formation and none of the studied variables alone could explain the large difference in the amount of plaque formed after 3 days between the "heavy" and "light" plaque formers.
本研究的目的是对两组菌斑形成速率不同的个体进行临床和生化特征分析。从133名个体中，挑选出9名“重度”菌斑形成者和10名“轻度”菌斑形成者。在双尖牙和第一磨牙颊面菌斑累积3天后，“重度”菌斑形成者的平均菌斑指数为2.6，“轻度”菌斑形成者为0.6。测定了以下变量：牙周状况、龋失补牙面数、饮食习惯、唾液分泌速率和缓冲作用、唾液中变形链球菌和乳酸菌计数、唾液中IgA、乳铁蛋白、乳过氧化物酶和溶菌酶的含量、唾液诱导的某些口腔链球菌聚集、唾液凝胶电泳、唾液、获得性膜的氨基酸组成以及龈牙区域的滞留深度。比较两组菌斑形成者，发现以下三个变量存在统计学显著差异：腮腺唾液诱导的一种血链球菌菌株聚集、获得性膜中谷氨酸含量以及上颌双尖牙的龈牙区域滞留深度。在组内和组间，所有研究变量均存在较大差异。菌斑形成可能涉及多个因素，所研究的变量单独一个都无法解释“重度”和“轻度”菌斑形成者在3天后菌斑形成量的巨大差异。
