Gluck J L, Myers J P, Pass L M
South Med J. 1987 Apr;80(4):511-3. doi: 10.1097/00007611-198704000-00024.
We have described a patient with cryptococcemia due to Cryptococcus albidus. Although usually nonpathogenic, C albidus and other non-neoformans cryptococcal species may occasionally be the causative agents in severe infections in man. The latex agglutination test for cryptococcal polysaccharide capsular antigen appears to be specific for C neoformans and thus may be falsely negative in serious infections caused by non-neoformans cryptococci, as seen in our patient with C albidus fungemia. Severe infections caused by C albidus appear to respond to treatment with amphotericin B with or without 5-fluorocytosine but so few cases are available for analysis that no firm conclusions can be made in this regard at present.
我们描述了一名因白色隐球菌感染导致隐球菌血症的患者。虽然白色隐球菌通常无致病性，但它以及其他非新生隐球菌菌种偶尔可能成为人类严重感染的病原体。针对隐球菌多糖荚膜抗原的乳胶凝集试验似乎对新生隐球菌具有特异性，因此在由非新生隐球菌引起的严重感染中可能出现假阴性结果，就像我们这位患有白色隐球菌菌血症的患者一样。白色隐球菌引起的严重感染似乎对两性霉素B联合或不联合5-氟胞嘧啶的治疗有反应，但可供分析的病例极少，以至于目前在这方面无法得出确凿结论。
