Center of Excellence in Catalysis for Bioenergy and Renewable Chemicals (CBRC), Faculty of Science, Chulalongkorn University, Pathum Wan, Bangkok 10330, Thailand.
Metallurgy and Materials Science Research Institute (MMRI), Chulalongkorn University, Bangkok 10330, Thailand.
Bioresour Technol. 2022 Jan;344(Pt B):126195. doi: 10.1016/j.biortech.2021.126195. Epub 2021 Oct 25.
Lignocellulosic biomass is a highly renewable, economical, and carbon-neutral feedstock containing sugar-rich moieties that can be processed to produce second-generation biofuels and bio-sourced compounds. However, due to their heterogeneous multi-scale structure, the lignocellulosic materials have major limitations to valorization and exhibit recalcitrance to saccharification or hydrolysis by enzymes. In this context, this review focuses on the latest methods available and state-of-the-art technologies in the pretreatment of lignocellulosic biomass, which aids the disintegration of the complex materials into monomeric units. In addition, this review deals with the genetic engineering techniques to develop advanced strategies for fermentation processes or microbial cell factories to generate desired products in native or modified hosts. Further, it also intends to bridge the gap in developing various economically feasible lignocellulosic products and chemicals using biorefining technologies.
木质纤维素生物质是一种极具可再生性、经济性和碳中性的原料，其中含有富含糖分的部分，可以经过加工生产第二代生物燃料和生物来源的化合物。然而，由于其异质的多尺度结构，木质纤维素材料在增值方面存在重大限制，并且对酶的糖化或水解表现出抗降解性。在这种情况下，本综述重点介绍了木质纤维素生物质预处理的最新方法和最先进的技术，这些方法有助于将复杂材料分解为单体单元。此外，本综述还涉及遗传工程技术，以开发先进的发酵工艺或微生物细胞工厂策略，在天然或改良宿主中生成所需的产品。此外，本综述还旨在利用生物炼制技术，弥合开发各种具有经济可行性的木质纤维素产品和化学品方面的差距。
