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坏死性胰腺炎:胰腺坏死感染中的一种不寻常病原体。

necrotizing pancreatitis: an unusual pathogen in pancreatic necrosis infection.

作者信息

Sánchez-Gollarte Ana, Jiménez-Álvarez Laura, Pérez-González Marina, Vera-Mansilla Cristina, Blázquez-Martín Alma, Díez-Alonso Manuel

机构信息

Department of General and Visceral Surgery, Hospital Universitario Príncipe de Asturias, Spain.

出版信息

Access Microbiol. 2021 Sep 15;3(9):000261. doi: 10.1099/acmi.0.000261. eCollection 2021.

Abstract

Pancreatic necrosis infection (PNI) accounts for about 20-40 % of severe acute pancreatitis. PNI caused by anaerobic bacteria is unusual but when they present, is the microorganism most commonly involved. We present a 60-year-old patient with a previous history of SARS-CoV-2, diagnosed with acute pancreatitis. During the hospitalisation he developed bacteraemia. A CT-scan showed pancreatic gas gangrene and a surgical necrosectomy was performed. was isolated in cultures of the pancreatic tissue and collections. The patient's clinical status improved after surgery and the appropriate medical therapy. He was discharged 76 days after admission. Nowadays, the 'step-up approach' is an accepted therapeutic tool in treatment of pancreatic necrosis and peripancreatic fluid collections. However, most authors suggest that infection requires a more aggressive approach due to the high mortality associated to clostridial infection.

摘要

胰腺坏死感染(PNI)约占重症急性胰腺炎的20%-40%。由厌氧菌引起的PNI并不常见,但一旦出现,厌氧菌是最常涉及的微生物。我们报告一名60岁有SARS-CoV-2既往史的患者,诊断为急性胰腺炎。住院期间他发生了菌血症。CT扫描显示胰腺气性坏疽,遂行外科坏死组织切除术。在胰腺组织培养物和采集物中分离出了(此处原文缺失具体细菌名称)。手术后及经过适当的药物治疗,患者的临床状况有所改善。入院76天后出院。如今,“逐步升级法”是治疗胰腺坏死和胰周液体积聚公认的治疗手段。然而,大多数作者认为,由于梭菌感染相关的高死亡率,(此处原文缺失具体细菌名称)感染需要采取更积极的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c79/8549386/0420f1babb39/acmi-3-0261-g001.jpg

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