Department of Medical Laboratory Science, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia.
Tigray Health Research Institute, Mekelle, Tigray, Ethiopia.
BMC Pediatr. 2021 Oct 29;21(1):480. doi: 10.1186/s12887-021-02960-1.
Anemia is a common complication of HIV/AIDS in children. There is lack of evidence on anemia prevalence among children living with HIV/AIDS on highly active antiretroviral therapy (HAART) in Tigray regional state, which the current study aimed to generate.
An institution-based cross-sectional study was conducted on 241 children living with HIV/AIDS on HAART attending the antiretroviral therapy (ART) clinic of Mekelle hospital from November 2018-January 2019. Socio-demographic data were collected using a structured pretested questionnaire. Participants' hemoglobin level was utilized to determine the prevalence of anemia. WHO cut-off values for Hgb were used to categorise the severity of anemia. Microscopic examination was performed for morphological classification of anemia.
Among the participants, 7 % (n = 16) were anemic in this study. Of these, 56 %, 19 %, and 25 % had mild, moderate, and severe anemia, respectively. Morphologically, normocytic-normochromic anemia was found the most common type of anemia in this study.
The prevalence of anemia among participants was low in this study. However, a considerable proportion of participants had severe anemia, requiring regular monitoring of anemia status in these patients for better clinical outcomes and quality of life improvements.
贫血是儿童 HIV/AIDS 的常见并发症。在提格雷州，针对接受高效抗逆转录病毒治疗（HAART）的 HIV/AIDS 儿童贫血患病率缺乏证据，本研究旨在对此进行研究。
2018 年 11 月至 2019 年 1 月，在梅开勒医院的抗逆转录病毒治疗（ART）诊所，对 241 名接受 HAART 的 HIV/AIDS 儿童进行了一项基于机构的横断面研究。使用结构化的预测试问卷收集社会人口统计学数据。参与者的血红蛋白水平用于确定贫血的患病率。世卫组织的 Hgb 临界值用于对贫血的严重程度进行分类。进行显微镜检查以对贫血进行形态学分类。
在参与者中，这项研究中有 7%（n=16）贫血。其中，56%、19%和 25%分别为轻度、中度和重度贫血。在形态学上，本研究中最常见的贫血类型为正细胞正色素性贫血。
在这项研究中，参与者的贫血患病率较低。然而，相当一部分参与者患有严重贫血，需要定期监测这些患者的贫血状况，以改善临床结局和提高生活质量。
