Desmond Tutu HIV Centre, Cape Town, South Africa.
Desmond Tutu HIV Centre, Faculty of Health Sciences, School of Medicine, University of Cape Town, Level 1, Wernher Beit North Building, Cape Town, 7505, South Africa.
AIDS Behav. 2022 May;26(5):1618-1632. doi: 10.1007/s10461-021-03514-3. Epub 2021 Oct 30.
While pre-exposure prophylaxis (PrEP) is a key HIV prevention tool for adolescents and young adults (AYAs), its initiation and sustained use is shaped by AYAs' unique social contexts, including family. We explored the role of families in AYAs' PrEP use through qualitative in-depth interview (IDI) data from iPrevent, an end-user study designed to identify factors that could optimize PrEP adherence among South African youth (18-24 years old). These data were collected using a semi structured guide and were analysed using an inductive approach. Several themes describing family influence on AYAs' PrEP use emerged including family support; family attitude towards PrEP; and the family's ability to obviate PrEP disclosure challenges. In addition, dimensions of family closeness, categorized as 'close', 'in-between' and 'loose-knit,' appeared important in contextualizing family influence on AYAs' PrEP use. We found that family remains a proximal and fundamental social system in which AYA are socialized and greater family engagement could aid PrEP implementation in this priority population.
虽然暴露前预防 (PrEP) 是青少年和年轻人 (AYAs) 的重要 HIV 预防工具，但它的启动和持续使用受到 AYAs 独特社会环境的影响，包括家庭。我们通过 iPrevent 的定性深入访谈 (IDI) 数据探讨了家庭在 AYAs 使用 PrEP 中的作用，iPrevent 是一项旨在确定可以优化南非青年 (18-24 岁) 接受 PrEP 依从性的因素的终端用户研究。这些数据是使用半结构化指南收集的，并采用归纳方法进行分析。出现了几个描述家庭对 AYAs 使用 PrEP 影响的主题，包括家庭支持；家庭对 PrEP 的态度；以及家庭避免 PrEP 披露挑战的能力。此外，家庭亲密关系的维度被归类为“亲密”、“中间”和“松散”，这在家庭对 AYAs 使用 PrEP 的影响方面显得很重要。我们发现，家庭仍然是 AYA 被社会化的一个近亲和基本的社会系统，更多的家庭参与可以帮助在这个优先人群中实施 PrEP。
