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国际功能、残疾和健康分类(ICF)在评估磁疗对新型冠状病毒肺炎相关病毒性肺炎患者有效性中的应用

[Application of the ICF in assessing the effectiveness of magnetotherapy in patients with viral pneumonia associated with COVID-19].

作者信息

Bodrova R A, Zakamyrdina A D, Fakhrutdinov I A, Dilyan A M, Mavzyutova R R, Kuchumova T V, Yunusova E R

机构信息

Kazan State Medical Academy - Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Healthcare of the Russian Federation, Kazan, Russia.

The Hospital for Veterans of Wars of Kazan of the Ministry of Health of Tatarstan, Kazan, Russia.

出版信息

Vopr Kurortol Fizioter Lech Fiz Kult. 2021;98(5):24-31. doi: 10.17116/kurort20219805124.

Abstract

UNLABELLED

The number of patients who have had pneumonia caused by COVID-19 is increasing every month. However, despite the ongoing treatment, the consequences of this disease are possible, which may appear in the short term or after a while. Pneumonia associated by the new coronavirus infection COVID-19 is characterized by the presence of such complications as cough, shortness of breath, fatigue, sleep disturbances, appetite disorders, etc. Often, pneumonia leads to dysfunctions of the respiratory system, higher mental functions, functions of the cardiovascular system and, unfortunately, possible disability. The search and implementation of new methods of physical rehabilitation is an urgent task of modern medicine. Low-frequency magnetotherapy is one of the safest and most commonly recommended treatments for pneumonia. The development of new methods of medical rehabilitation for patients with pneumonia associated with COVID-19, using physical factors such as low-frequency magnetotherapy, laser therapy is one of the leading fields. Magnetotherapy is included in the recommendations of the Ministry of Health of the Russian Federation for the purpose of anti-inflammatory, decongestant, reparative-regenerative action; improvement of microcirculation, acceleration of the resorption of infiltrative changes (Temporary methodological recommendations «Medical rehabilitation for a new coronavirus infection (COVID-19)», version 2 of 31.07.2020). International rehabilitation practice of using the International Classification of Functioning, Disability and Health (ICF) advises to use it as a tool that allows you to objectively determine the state of health of patients, determine the prognosis of impaired functions and evaluate the effectiveness of ongoing rehabilitation measures.

OBJECTIVE

To assess the effectiveness of the use of low-frequency magnetotherapy in the complex medical rehabilitation of patients who have had pneumonia in the phase of convalescence according to the International Classification of Functioning, Disability and Health.

MATERIAL AND METHODS

The study included 200 patients who had suffered from pneumonia associating by COVID-19 and whose average age was 54.3±5.8 years. 1 (main) group (=100), against the background of standard therapy on the 16th day after discharge from the hospital, received low-frequency magnetotherapy on the ALMAG-02 apparatus («Elamed», Russia) daily for 10-20 minutes, a course of 15 procedures. The 2 group(control) included 100 patients who underwent low-frequency placebo-magnetotherapy on the ALMAG-02 apparatus («Elamed», Russia). In order to assess the dynamics of clinical and laboratory data and the effectiveness of treatment, control methods were used in this study in accordance with the Temporary Clinical Recommendations of the Ministry of Health of the Russian Federation. Each patient was evaluated for the severity of the initial manifestations of respiratory failure using the mMRC scale (Degree of Shortness of breath) and the Borg scale, and the quality of life of patients was assessed on the EQ-5D scale. Also, at the time of inclusion in the study and during the control examination after the completion of prospective follow-up, the Individual profile of patients was determined in accordance with the international classification of functioning (ICF) with the data of the «Individual Registration Card of the clinical trial participant».

RESULTS AND DISCUSSION

In 43% (43 people) of patients of the 1th group, an improvement in respiration functions was noted with lung auscultation and with spirometry, an increase in the vital capacity of the lungs by 28.2% (=0.0021), an increase in chest excursion by 53.1% (=0.0019) a decrease in the level of shortness of breath by 50% and Borg by 33.3% (=0.0016). According to the data of the quality of life questionnaire (EQ-5D), the patients of the main group showed an improvement in the quality of life by 23% (=0.0019). In the 1 group of patients, there was a decrease in moderate disorders in the domains «b152 - emotion functions» in 45% of patients; «b440 - respiratory functions» in 87% of patients; «b455 - exercise tolerance functions» in 74% of patients; «b134 - sleep functions» in 30% of patients; «d450 - walking» in 100% of patients. In the general blood analysis of patients of the 1 (main) group, there was a relief of leukocytosis, normalization of the erythrocyte sedimentation rate (ESR). In the 1 group a decrease in the duration of being on the sick list was observed for 3.4±0.2 days.

CONCLUSION

The inclusion of low-frequency magnetic therapy in the complex rehabilitation of patients who have suffered pneumonia associated by COVID-19 contributes to improving the function of external respiration of patients, regression of residual infiltrative changes in the lungs after pneumonia, relief of residual manifestations of the inflammatory process, reducing the duration of the rehabilitation period and the duration of disability, improving the general well-being of patients, increasing tolerance to physical exertion, normalization of the psycho-emotional state and, as a result,, restoring activity in everyday life and improving the quality of life of patients. The researchers did not register any side effects and side effects of magnetic therapy from ALMAG-02 apparatus (Elamed, Russia).

摘要

未标注

感染新冠病毒导致肺炎的患者数量每月都在增加。然而,尽管持续进行治疗,该疾病仍可能产生后果,这些后果可能在短期内或一段时间后出现。新型冠状病毒感染新冠病毒相关的肺炎的特征是存在咳嗽、呼吸急促、疲劳、睡眠障碍、食欲紊乱等并发症。通常,肺炎会导致呼吸系统、高级心理功能、心血管系统功能障碍,不幸的是,还可能导致残疾。寻找并应用新的物理康复方法是现代医学的一项紧迫任务。低频磁疗是治疗肺炎最安全、最常用的推荐疗法之一。利用低频磁疗、激光疗法等物理因素为感染新冠病毒相关肺炎患者开发新的医学康复方法是前沿领域之一。磁疗被列入俄罗斯联邦卫生部的建议中,用于抗炎、消肿、修复再生;改善微循环、加速浸润性改变的吸收(《新型冠状病毒感染(COVID - 19)的医学康复临时方法建议》,2020年7月31日第2版)。使用国际功能、残疾和健康分类(ICF)的国际康复实践建议将其用作一种工具,以便客观地确定患者的健康状况、确定功能受损的预后并评估正在进行的康复措施的效果。

目的

根据国际功能、残疾和健康分类评估低频磁疗在肺炎康复期患者综合医学康复中的有效性。

材料与方法

该研究纳入了200名感染新冠病毒相关肺炎的患者,平均年龄为54.3±5.8岁。第1(主要)组(=100人)在出院后第16天,在标准治疗的基础上,使用ALMAG - 02仪器(俄罗斯“Elamed”)进行低频磁疗,每天10 - 20分钟,共15次疗程。第2组(对照组)包括100名在ALMAG - 02仪器(俄罗斯“Elamed”)上接受低频安慰剂磁疗的患者。为了评估临床和实验室数据的动态变化以及治疗效果,本研究根据俄罗斯联邦卫生部的临时临床建议使用了对照方法。使用mMRC量表(呼吸急促程度)和博格量表评估每位患者呼吸衰竭初始表现的严重程度,并使用EQ - 5D量表评估患者的生活质量。此外,在纳入研究时以及前瞻性随访完成后的对照检查期间,根据国际功能分类(ICF)和“临床试验参与者个人注册卡”的数据确定患者的个人档案。

结果与讨论

第1组43%(43人)的患者在肺部听诊和肺功能检查时呼吸功能有所改善,肺容量增加28.2%(=0.0021),胸廓活动度增加53.1%(=0.0019),呼吸急促程度降低50%,博格量表评分降低33.3%(=0.0016)。根据生活质量问卷(EQ - 5D)的数据,主要组患者的生活质量提高了23%(=0.0019)。在第1组患者中,45%的患者在“b152 - 情绪功能”领域的中度障碍有所减少;87%的患者在“b[440 - 呼吸功能”领域;74%的患者在“b455 - 运动耐力功能”领域;30%的患者在“b134 - 睡眠功能”领域;100%的患者在“d450 - 行走”领域。在第1(主要)组患者的血常规分析中,白细胞增多症得到缓解,红细胞沉降率(ESR)恢复正常。第1组患者的病假天数减少了3.4±0.2天。

结论

将低频磁疗纳入感染新冠病毒相关肺炎患者的综合康复中,有助于改善患者的外呼吸功能,使肺炎后肺部残留浸润性改变消退,缓解炎症过程的残留表现,缩短康复期和残疾持续时间,改善患者的总体健康状况,增加对体力活动的耐受性,使心理情绪状态正常化,从而恢复日常生活活动能力并提高患者的生活质量。研究人员未发现来自ALMAG - 02仪器(俄罗斯“Elamed”)的磁疗有任何副作用和不良反应。

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