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主动脉夹层继发脊髓缺血:病例报告及不同临床表现、危险因素、影像学表现、治疗方式和结局的文献综述

Spinal Cord Ischemia Secondary to Aortic Dissection: Case Report with Literature Review for Different Clinical Presentations, Risk Factors, Radiological Findings, Therapeutic Modalities, and Outcome.

作者信息

Elshony Hosna, Idris Abdelrahman, Ahmed Alaa, Almaghrabi Murouj, Ahmed Walaa, Fallatah Shouq

机构信息

Department of Neuropsychiatry, Faculty of Medicine, Menoufia University, Shebin El Kom, Egypt.

Department of Neurology/Internal medicine, Security Forces Hospital, Makkah, Saudi Arabia.

出版信息

Case Rep Neurol. 2021 Sep 28;13(3):634-655. doi: 10.1159/000518197. eCollection 2021 Sep-Dec.

DOI:10.1159/000518197
PMID:34720966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8543361/
Abstract

Aortic dissection (AD) is a serious condition that causes transient or permanent neurological problems that include spinal cord ischemia (SCI), which occurs when AD extends into the descending aorta resulting in insufficient perfusion of segmental arteries that supplies the spinal cord. We report a 64-year-old male, presented with severe back pain, asymmetrical paresthesia, and weakness of both limbs, more in the left lower limb with loss of pinprick, temperature, and fine touch sensation on the lower left lower limb below the level of T5 with preserved proprioception and vibration and urine hesitancy. Computed tomography showed AD, Stanford type A, and spinal magnetic resonance imaging (MRI) showed hyperintense owl's eye sign at T5. The patient was diagnosed as anterior spinal artery syndrome secondary to an AD and referred for aortic surgical repair with good functional outcome. In our review to cases of SCI due to AD, it was more common in males above 55 years, pain only found in 47.8% of patients, with anterior cord syndrome on top of the clinical presentations, and hypertension is the most common risk factor. MRI spine showed thoracic location predominance. Surgical or endovascular repair especially for type A and complicated type B should be considered to avoid complications, and cerebrospinal fluid drainage is a very useful tool in reversing SCI specially if done early with favorable outcome. Only the old age is associated with increased risk of mortality. Early diagnosis and appropriate management are crucial for better outcome.

摘要

主动脉夹层(AD)是一种严重疾病,可导致短暂或永久性神经问题,包括脊髓缺血(SCI),当AD延伸至降主动脉时会发生脊髓缺血,导致供应脊髓的节段动脉灌注不足。我们报告一例64岁男性,表现为严重背痛、不对称感觉异常和双下肢无力,左下肢更明显,T5水平以下左下肢针刺觉、温度觉和精细触觉丧失,本体感觉和振动觉保留,伴有尿踌躇。计算机断层扫描显示为斯坦福A型AD,脊柱磁共振成像(MRI)显示T5处有高信号“猫头鹰眼”征。该患者被诊断为继发于AD的脊髓前动脉综合征,并转诊接受主动脉手术修复,功能预后良好。在我们对AD所致SCI病例的回顾中,该病在55岁以上男性中更常见,仅47.8%的患者有疼痛,临床表现以脊髓前综合征为主,高血压是最常见的危险因素。脊柱MRI显示以胸段为主。应考虑手术或血管内修复,尤其是对A型和复杂B型,以避免并发症,脑脊液引流是逆转SCI的非常有用的手段,特别是早期进行时效果良好。只有高龄与死亡风险增加相关。早期诊断和适当治疗对获得更好的预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/249c7f04021e/crn-0013-0634-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/142bbf9be67f/crn-0013-0634-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/d29bc18b8ba4/crn-0013-0634-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/0a90a7b7b7aa/crn-0013-0634-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/249c7f04021e/crn-0013-0634-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/142bbf9be67f/crn-0013-0634-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/d29bc18b8ba4/crn-0013-0634-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/0a90a7b7b7aa/crn-0013-0634-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/8543361/249c7f04021e/crn-0013-0634-g04.jpg

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