Waldron C A, el-Mofty S K
Oral Surg Oral Med Oral Pathol. 1987 Apr;63(4):441-51. doi: 10.1016/0030-4220(87)90257-x.
The histopathologic features of 116 ameloblastomas were reviewed with special reference to the incidence of the recently described desmoplastic variant. The series included 110 intraosseous lesions and 6 extraosseous ameloblastomas. Ninety-six (88%) of the intraosseous tumors were found in the mandible, and 61% involved the molar-ascending ramus area. Fourteen examples of the desmoplastic variant were identified, representing 13% of the intraosseous tumors. The lesions showed distinctive histologic features characterized by an extensive collagenized stroma containing small islands of tumor epithelium with scant tendency to form cystic structures. This histologic variant has a marked tendency to involve the anterior portions of the jaws with 7 of the 14 examples being located in the maxilla. These desmoplastic lesions also showed unusual radiographic findings, often more suggestive of a benign fibro-osseous lesion than of ameloblastoma.
回顾了116例成釉细胞瘤的组织病理学特征，特别关注最近描述的促结缔组织增生性变异型的发生率。该系列包括110例骨内病变和6例骨外成釉细胞瘤。骨内肿瘤中有96例（88%）发生在下颌骨，61%累及磨牙-升支区。确定了14例促结缔组织增生性变异型，占骨内肿瘤的13%。病变表现出独特的组织学特征，其特点是广泛的胶原化间质，含有小的肿瘤上皮岛，形成囊性结构的倾向很小。这种组织学变异型有明显累及颌骨前部的倾向，14例中有7例位于上颌骨。这些促结缔组织增生性病变还表现出不寻常的影像学表现，通常更提示良性纤维-骨病变而非成釉细胞瘤。
