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1
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Anesth Prog. 1987 Jan-Feb;34(1):6-9.
2
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Long-acting analgesic or long-acting local anesthetic in controlling immediate postoperative pain after lower third molar surgery.长效镇痛药或长效局部麻醉药用于控制下颌第三磨牙手术后的即时疼痛。
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4
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Preoperative intravenous tramadol versus diclofenac for preventing postoperative pain after third molar surgery: a comparative study.术前静脉注射曲马多与双氯芬酸预防第三磨牙手术后疼痛的比较研究
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8
Comparison between lidocaine and bupivacaine as local anesthetics with diflunisal for postoperative pain control after lower third molar surgery.利多卡因和布比卡因作为局部麻醉剂与双氟芬酸联合用于下颌第三磨牙手术后疼痛控制的比较。
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本文引用的文献

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CONTROL OF POSTOPERATIVE SEQUELAE IN IMPACTED THIRD MOLAR SURGERY.
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2
THE ENZYMATIC FORMATION OF PROSTAGLANDIN E2 FROM ARACHIDONIC ACID PROSTAGLANDINS AND RELATED FACTORS 32.从花生四烯酸形成前列腺素E2的酶促过程 前列腺素及相关因子32
Biochim Biophys Acta. 1964 Jul 15;90:207-10. doi: 10.1016/0304-4165(64)90145-x.
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THE BIOSYNTHESIS OF PROSTAGLANDINS.前列腺素的生物合成
Biochim Biophys Acta. 1964 Jul 15;90:204-7. doi: 10.1016/0304-4165(64)90144-8.
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A 12-hour evaluation of the analgesic efficacy of diflunisal, aspirin, and placebo in postoperative dental pain.双氟尼酸、阿司匹林和安慰剂对术后牙痛镇痛效果的12小时评估。
J Clin Pharmacol. 1982 Feb-Mar;22(2-3):89-96. doi: 10.1002/j.1552-4604.1982.tb02654.x.
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Effect of preoperative paracetamol on pain after oral surgery.术前使用对乙酰氨基酚对口腔手术后疼痛的影响。
Eur J Clin Pharmacol. 1983;24(1):63-5. doi: 10.1007/BF00613928.
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Clinical comparison of the analgesic efficacy of suprofen, diflunisal and placebo in the treatment of pain after meniscectomy.
Pharmacology. 1983;27 Suppl 1:74-80. doi: 10.1159/000137902.
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Suppression of postoperative pain by preoperative administration of ibuprofen in comparison to placebo, acetaminophen, and acetaminophen plus codeine.与安慰剂、对乙酰氨基酚以及对乙酰氨基酚加可待因相比，术前给予布洛芬对术后疼痛的抑制作用。
J Clin Pharmacol. 1983 Jan;23(1):37-43. doi: 10.1002/j.1552-4604.1983.tb02702.x.
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The visual analog scale in multiple-dose evaluations of analgesics.
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Recovery of prostaglandins in human cutaneous inflammation.人类皮肤炎症中前列腺素的恢复情况。
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Indomethacin and aspirin abolish prostaglandin release from the spleen.吲哚美辛和阿司匹林可抑制前列腺素从脾脏释放。
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长效镇痛药或长效局部麻醉药用于控制下颌第三磨牙手术后的即刻疼痛。

Long-acting analgesic or long-acting local anesthetic in controlling immediate postoperative pain after lower third molar surgery.

作者信息

Rosenquist J B, Nystrom E

出版信息

Anesth Prog. 1987 Jan-Feb;34(1):6-9.

PMID:3472476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2186224/
Abstract

In a double-blind crossover study, the effect on postoperative pain of lidocaine plus diflunisal was compared with that of bupivacaine and placebo. Forty-eight patients with bilateral impactions of lower third molars had these removed on two occasions four weeks apart. One pain-control regimen was used on one occasion and the alternate on the second. The pain intensity was indicated on a visual analog scale at 2, 3, 4, 5, and 6 hours postoperatively. The pain values for the first postoperative hours were higher for the lidocaine diflunisal combination, whereas after 5 hours the opposite was true. Significantly more patients preferred the combination of lidocaine and diflunisal. Three patients reported fatigue postoperatively during the day of surgery, which they attributed to the operation and not to the analgesics used.

摘要

在一项双盲交叉研究中，将利多卡因加双氟尼酸对术后疼痛的影响与布比卡因和安慰剂进行了比较。48例双侧下颌第三磨牙阻生患者分两次拔除，两次间隔四周。一次使用一种疼痛控制方案，另一次使用另一种。术后2、3、4、5和6小时通过视觉模拟量表指示疼痛强度。术后最初几个小时，利多卡因与双氟尼酸联合使用时疼痛值较高，而5小时后情况相反。明显更多患者更喜欢利多卡因和双氟尼酸的组合。3例患者在手术当天术后报告疲劳，他们将其归因于手术而非所用的镇痛药。