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布比卡因加肾上腺素与碳酸布比卡因加肾上腺素用于下颌阻生第三磨牙拔除术的比较研究

A Comparative Study Between Bupivacaine with Adrenaline and Carbonated Bupivacaine with Adrenaline for Surgical Removal of Impacted Mandibular Third Molar.

作者信息

Shyamala M, Ramesh C, Yuvaraj V, Suresh V, SathyaNarayanan R, Balaji T S, Neil Dominic M, Nithin Joseph Jude B

机构信息

Department of Oral and Maxillofacial Surgery, Indira Gandhi Institute of Dental Sciences, Cuddalore Main Road, Pillaiyarkuppam Post Office, Puducherry, 607402 India.

出版信息

J Maxillofac Oral Surg. 2016 Mar;15(1):99-105. doi: 10.1007/s12663-015-0791-4. Epub 2015 May 29.

Abstract

OBJECTIVES

To compare the effectiveness of bupivacaine with adrenaline with that of carbonated bupivacaine with adrenaline on pain, onset of anesthesia and duration of anesthesia following surgical removal of impacted mandibular third molar.

STUDY DESIGN

All the patients who underwent surgical removal of impacted mandibular third molar and who fulfilled our inclusion and exclusion criteria from 1st June 2013 to 30th June 2014 were included in our study. Patients who were diagnosed as having impacted mandibular third molar were randomly allocated to two groups namely group A (bupivacaine with adrenaline), group B (carbonated bupivacaine with adrenaline). Pain during deposition of local anesthetic, onset of anesthesia and duration of anesthesia were compared between the two groups. The collected data were subjected to statistical analysis by Chi Square test, Mann-Whitney U test.

RESULTS AND CONCLUSION

The efficacy of carbonated bupivacaine with adrenaline is more compared with bupivacaine with adrenaline in decreasing pain on deposition of local anesthetic solution and in rapid onset of anesthesia. The duration of anesthesia for carbonated bupivacaine with adrenaline and bupivacaine with adrenaline had no significant difference. The use of carbonated bupivacaine with adrenaline will reduce the patient discomfort both intra-operatively and post-operatively.

摘要

目的

比较布比卡因加肾上腺素与碳酸布比卡因加肾上腺素在拔除下颌阻生第三磨牙术后疼痛、麻醉起效时间及麻醉持续时间方面的效果。

研究设计

纳入2013年6月1日至2014年6月30日期间接受下颌阻生第三磨牙拔除手术且符合纳入和排除标准的所有患者。将诊断为下颌阻生第三磨牙的患者随机分为两组,即A组(布比卡因加肾上腺素)和B组(碳酸布比卡因加肾上腺素)。比较两组在局部麻醉药注射时的疼痛、麻醉起效时间及麻醉持续时间。对收集的数据采用卡方检验、曼-惠特尼U检验进行统计分析。

结果与结论

与布比卡因加肾上腺素相比,碳酸布比卡因加肾上腺素在减轻局部麻醉药注射时的疼痛及快速起效方面效果更佳。碳酸布比卡因加肾上腺素与布比卡因加肾上腺素的麻醉持续时间无显著差异。使用碳酸布比卡因加肾上腺素可减轻患者术中及术后的不适。

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