Singh Achintya, Ford Andrew M, McMichael John, Gabbard Scott
Internal Medicine, Cleveland Clinic Foundation, Cleveland, USA.
General Surgery, Cleveland Clinic Foundation, Cleveland, USA.
Cureus. 2021 Sep 28;13(9):e18343. doi: 10.7759/cureus.18343. eCollection 2021 Sep.
Post-fundoplication dyspepsia is a common complication of gastric fundoplication surgeries. This can be attributable to the loss of fundal relaxation, decreased gastric accommodation, and/or alterations in gastric motility and sensitivity following fundoplication. The role of neuromodulators in the management of such symptoms is unknown. We retrospectively assessed the efficacy of neuromodulators such as tricyclic antidepressants, buspirone, and mirtazapine for the management of post-fundoplication dyspepsia.
胃底折叠术后消化不良是胃底折叠术常见的并发症。这可能归因于胃底松弛功能丧失、胃容纳能力下降和/或胃底折叠术后胃动力及敏感性改变。神经调节剂在这类症状管理中的作用尚不清楚。我们回顾性评估了三环类抗抑郁药、丁螺环酮和米氮平等神经调节剂治疗胃底折叠术后消化不良的疗效。
