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同卵双生子中特发性粗甲症的同时发生。

Simultaneous occurrence of idiopathic trachyonychia in dizygotic twins.

机构信息

Department of Dermatology, University of Connecticut, Farmington, CT, USA.

Department of Pediatrics, University of Connecticut, Farmington, CT, USA.

出版信息

Pediatr Dermatol. 2021 Nov;38(6):1586-1587. doi: 10.1111/pde.14847. Epub 2021 Nov 1.

Abstract

Trachyonychia (or twenty-nail dystrophy) is an uncommon chronic disorder manifesting as thin, flattened, brittle nails with excessive longitudinal ridging and loss of luster creating a "sandpaper-like" texture that most commonly presents spontaneously in childhood as an isolated phenomenon; however, it has been historically associated with numerous dermatoses. Rarely, trachyonychia has been reported to occur in families, suggesting a potential hereditary predisposition. We report trachyonychia occurring simultaneously in dizygotic twins, further supporting a possible underlying genetic basis of this idiopathic nail disorder.

摘要

甲纵嵴(或二十甲营养不良)是一种罕见的慢性疾病,表现为薄、平、脆的指甲,有过多的纵向脊和失去光泽,形成“砂纸样”质地,这种情况最常见于儿童时期,表现为孤立现象;然而,它在历史上与许多皮肤病有关。很少有报道称甲纵嵴发生在家族中,提示可能存在潜在的遗传易感性。我们报告了在同卵双胞胎中同时发生的甲纵嵴,这进一步支持了这种特发性指甲疾病可能存在潜在的遗传基础。

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