Department of Dermatology, University of Connecticut, Farmington, CT, USA.
Department of Pediatrics, University of Connecticut, Farmington, CT, USA.
Pediatr Dermatol. 2021 Nov;38(6):1586-1587. doi: 10.1111/pde.14847. Epub 2021 Nov 1.
Trachyonychia (or twenty-nail dystrophy) is an uncommon chronic disorder manifesting as thin, flattened, brittle nails with excessive longitudinal ridging and loss of luster creating a "sandpaper-like" texture that most commonly presents spontaneously in childhood as an isolated phenomenon; however, it has been historically associated with numerous dermatoses. Rarely, trachyonychia has been reported to occur in families, suggesting a potential hereditary predisposition. We report trachyonychia occurring simultaneously in dizygotic twins, further supporting a possible underlying genetic basis of this idiopathic nail disorder.
甲纵嵴(或二十甲营养不良)是一种罕见的慢性疾病,表现为薄、平、脆的指甲,有过多的纵向脊和失去光泽,形成“砂纸样”质地,这种情况最常见于儿童时期,表现为孤立现象;然而,它在历史上与许多皮肤病有关。很少有报道称甲纵嵴发生在家族中,提示可能存在潜在的遗传易感性。我们报告了在同卵双胞胎中同时发生的甲纵嵴,这进一步支持了这种特发性指甲疾病可能存在潜在的遗传基础。