Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA
Research and Development, Talkspace Network LLC, New York City, New York, USA.
BMJ Open. 2021 Nov 2;11(11):e046958. doi: 10.1136/bmjopen-2020-046958.
Digital mental health tools have become popular alternatives to traditional psychotherapy. One emerging form of digital mental health is message-based care, the use of text messages or asynchronous voice or video messaging to provide psychotherapy. There has been no research into whether this is an effective method of psychotherapy as a stand-alone treatment or in combination with traditional psychotherapy.
This is a sequential, multiple assignment randomised trial to compare message-based care, videoconference-psychotherapy and a combination of the two treatments in 1000 depressed adults. Participants will be recruited through Talkspace, a digital mental health company, and randomised to receive 6 weeks of either message-based care only or videoconference-psychotherapy only. At 6 weeks, participants will be evaluated for their response to treatment. Those with a 50% or more response to treatment will continue with their assigned condition. Those who do not respond will be randomised to either monthly videoconference-psychotherapy or weekly videoconference-psychotherapy plus message-based care. Primary outcomes will be depression and social functioning. We will also explore moderators of treatment outcome.
The study received ethics approval from the University of Washington Institutional Review Board. Results of this study will be presented in peer-reviewed journals and at professional conferences.
NCT04513080; Pre-results.
数字心理健康工具已成为传统心理治疗的热门替代选择。一种新兴的数字心理健康形式是基于消息的护理，即使用短信或异步语音或视频消息传递来提供心理治疗。目前还没有研究表明，这种作为独立治疗或与传统心理治疗相结合的心理治疗方法是否有效。
这是一项序贯、多次分配随机试验，旨在比较基于消息的护理、视频会议心理治疗以及这两种治疗方法的联合应用在 1000 名抑郁成年人中的效果。参与者将通过数字心理健康公司 Talkspace 招募，并随机分配接受 6 周的基于消息的护理或视频会议心理治疗。在 6 周时，将对参与者的治疗反应进行评估。对治疗有 50%或更多反应的患者将继续接受其指定的治疗。对治疗无反应的患者将被随机分配到每月一次的视频会议心理治疗或每周一次的视频会议心理治疗加基于消息的护理。主要结局将是抑郁和社会功能。我们还将探讨治疗结果的调节因素。
该研究已获得华盛顿大学机构审查委员会的伦理批准。这项研究的结果将在同行评议的期刊和专业会议上发表。
NCT04513080；预结果。
