Zhang Hanlin, Zhang Dingyue, Tang Keyun, Sun Qiuning
Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Skin and Immune Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People's Republic of China.
Clin Cosmet Investig Dermatol. 2021 Oct 24;14:1551-1560. doi: 10.2147/CCID.S322530. eCollection 2021.
Alzheimer's disease is the most common type of dementia placing a heavy burden on the healthcare system worldwide. Skin diseases are also one of the most common health problems. Several skin diseases are associated with Alzheimer's disease through different mechanisms. This review summarizes the relationship between Alzheimer's disease and several types of skin diseases, including bullous pemphigoid, hidradenitis suppurativa, psoriasis, skin cancer, and cutaneous amyloidosis, and provides suggestions based on these associations. Neurologists, dermatologists, and general practitioners should be aware of the relationship between Alzheimer's disease and skin diseases. Dermatology/neurology consultation or referral is necessary when needed.
阿尔茨海默病是最常见的痴呆类型,给全球医疗系统带来了沉重负担。皮肤病也是最常见的健康问题之一。几种皮肤病通过不同机制与阿尔茨海默病相关。本综述总结了阿尔茨海默病与几种皮肤病之间的关系,包括大疱性类天疱疮、化脓性汗腺炎、银屑病、皮肤癌和皮肤淀粉样变性,并基于这些关联提出了建议。神经科医生、皮肤科医生和全科医生应了解阿尔茨海默病与皮肤病之间的关系。必要时需进行皮肤科/神经科会诊或转诊。