Moore Jonathan, Mahajan Akhilesh, Gajjala Sravani, Makkar Priyanka
Pulmonary and Critical Care, Lenox Hill Hospital, New York, USA.
Internal Medicine, Lenox Hill Hospital, New York, USA.
Cureus. 2021 Oct 1;13(10):e18427. doi: 10.7759/cureus.18427. eCollection 2021 Oct.
We describe an interesting rare case of a 61-year-old woman who was admitted to our hospital for exertional dyspnea, non-productive cough, and generalized weakness of six months duration. Her computed tomography was significant for ground-glass opacities combined with bibasilar consolidations and numerous pulmonary cysts. There can be a significant overlap in imaging findings of post-coronavirus disease 2019 (COVID-19) lung disease and interstitial lung disease from autoimmune diseases. We review in extensive detail the differential diagnosis for these imaging findings from a pulmonologist's perspective and discuss investigations required for further workup. Our patient underwent transbronchial biopsy and was eventually diagnosed with lymphocytic interstitial pneumonia with Sjogren predominant mixed connective tissue disease. We also review in detail the current literature and prognosis for this interesting disease.
我们描述了一例有趣的罕见病例，一名61岁女性因劳力性呼吸困难、干咳和持续6个月的全身无力入住我院。她的计算机断层扫描显示有显著的磨玻璃影，伴有双肺基底实变和大量肺囊肿。2019冠状病毒病（COVID-19）肺部疾病和自身免疫性疾病所致间质性肺疾病的影像学表现可能有显著重叠。我们从肺科医生的角度详细回顾了这些影像学表现的鉴别诊断，并讨论了进一步检查所需的调查。我们的患者接受了经支气管活检，最终被诊断为以干燥综合征为主的混合性结缔组织病合并淋巴细胞间质性肺炎。我们还详细回顾了关于这种有趣疾病的当前文献和预后情况。
