Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Programa de Pós-Graduação em Saúde Coletiva. Campinas, SP, Brasil.
Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Departamento de Tocoginecologia. Campinas, SP, Brasil.
Rev Saude Publica. 2021 Oct 29;55:67. doi: 10.11606/s1518-8787.2021055003085. eCollection 2021.
To analyze the magnitude of changes in the incidence and mortality from cervical cancer (CC) and breast cancer (BC) in Campinas, São Paulo State, between the five-year periods of 1991-1995 and 2010-2014.
data on cancer were obtained from the Campinas Population-Based Cancer Registry and data on deaths from the Mortality Information System of the Computing Department of the Unified Health System. Age-standardized incidence and mortality rates were calculated by the direct method, with the respective 95% confidence intervals. The magnitude of the changes was measured by the rate ratio (rate ratio; 95%CI).
among the periods studied, there was a threefold increase in the detection rate of in situ CC (3.03; 95%CI: 2.64-3.47) and fivefold increase for in situ BC (5.23; 95%CI: 4.98-5.50). The proportion of cases of in situ BC in relation to the total number of cases of BC increased from 3.31% to 11.05%. The incidence rate of invasive CC decreased by 57% (0.43; 95%CI: 0.40-0.47), and the incidence rate of invasive BC increased by 40% (1.40; 95%CI: 1.33-1.47). The mortality rate of the CC decreased by 58% (0.42; 95%CI: 0.32-0.56), and that of BC by 15% (0.85; 95%CI: 0.82-0.89).
the incidence of in situ carcinomas of CC and BC increased in almost two decades. The rate of invasive carcinoma of CC decreased, and that of BC increased. Mortality from both cancers decreased. Observing these changes is useful for assessing the impact of the actions carried out in the period and for planning future actions.
分析圣保罗州坎皮纳斯市在 1991-1995 年和 2010-2014 年这两个五年期间宫颈癌（CC）和乳腺癌（BC）发病率和死亡率的变化幅度。
癌症数据来自坎皮纳斯人群癌症登记处，死亡数据来自统一卫生系统计算部门的死亡率信息系统。采用直接法计算年龄标准化发病率和死亡率，并计算各自的 95%置信区间。变化幅度通过率比（rate ratio）进行测量（率比；95%CI）。
在所研究的时期内，原位 CC 的检出率增加了两倍（3.03；95%CI：2.64-3.47），原位 BC 的检出率增加了五倍（5.23；95%CI：4.98-5.50）。原位 BC 病例在 BC 总病例中的比例从 3.31%增加到 11.05%。浸润性 CC 的发病率下降了 57%（0.43；95%CI：0.40-0.47），浸润性 BC 的发病率增加了 40%（1.40；95%CI：1.33-1.47）。CC 的死亡率下降了 58%（0.42；95%CI：0.32-0.56），BC 的死亡率下降了 15%（0.85；95%CI：0.82-0.89）。
近二十年，CC 和 BC 的原位癌发病率增加。CC 的浸润性癌发病率下降，BC 的发病率上升。两种癌症的死亡率都下降了。观察这些变化有助于评估该时期开展的各项行动的影响，并为未来的行动规划提供参考。
