Lee Sam Yong, Kim Woo Hyeong, Choi Jun Ho, Kim Kwang Seog, Hwang Jae Ha
Department of Plastic and Reconstructive Surgery, Chonnam National University Medical School, Gwangju, Korea.
Arch Craniofac Surg. 2021 Oct;22(5):280-284. doi: 10.7181/acfs.2021.00472. Epub 2021 Oct 20.
Primary cutaneous marginal zone B-cell lymphoma (PCMZL) is an uncommon type of malignant lymphoma that mainly occurs in the trunk and upper extremity, with less frequent incidence observed on the head. Herein, we report the early diagnosis and treatment of a rare case of facial PCMZL in an Asian patient. A 51-year-old man presented with masses on the forehead and nose tip, which he had incidentally discovered 2 months previously. The masses appeared as a papule on the forehead and a patch on the nose. There were no signs of infection or bleeding, and the patient reported no other symptoms. After complete surgical excision, PCMZL was diagnosed based on the permanent biopsy. The histopathological findings revealed lymphoid aggregations with multifocal granulomas. Further treatment and follow-up were conducted at the hematology and oncology department. Despite its rarity in Asian populations, cutaneous lymphoma should be included in the differential diagnosis of facial masses. Early diagnosis and treatment based on a physical examination, imaging study, and excisional biopsy are important for a favorable prognosis.
原发性皮肤边缘区B细胞淋巴瘤（PCMZL）是一种罕见的恶性淋巴瘤，主要发生于躯干和上肢，头部发病率较低。在此，我们报告1例亚洲面部PCMZL罕见病例的早期诊断和治疗情况。一名51岁男性患者，前额和鼻尖出现肿物，2个月前偶然发现。肿物在前额表现为丘疹，在鼻尖表现为斑片。无感染或出血迹象，患者也无其他症状。完整手术切除后，根据永久活检确诊为PCMZL。组织病理学检查结果显示淋巴样聚集伴多灶性肉芽肿。随后在血液学和肿瘤学科室进行了进一步治疗及随访。尽管皮肤淋巴瘤在亚洲人群中罕见，但在面部肿物的鉴别诊断中应考虑该病。基于体格检查、影像学检查和切除活检进行早期诊断和治疗，对获得良好预后至关重要。
