Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Am J Gastroenterol. 2021 Nov 1;116(11):2296-2299. doi: 10.14309/ajg.0000000000001502.
Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.
We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.
Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.
Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.
外阴受累是克罗恩病（CD）的罕见并发症。外阴 CD 的最佳治疗方法尚不清楚。
我们对 3 个转诊中心的外阴 CD 进行了为期 25 年的回顾性队列研究。研究了临床特征和结局。
共确定了 50 名患者。最常见的外阴症状是疼痛（74%）、肿胀（60%）、溃疡（46%）、结节（36%）和脓肿（34%）。导致症状改善的药物治疗各不相同，有 5 名患者最终需要手术。
外阴 CD 表现出广泛的症状。尽管有 10%的病例需要手术，但积极的药物治疗通常是有效的。
