外阴克罗恩病：临床特征和结局。
Vulvar Crohn's Disease: Clinical Features and Outcomes.
机构信息
Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
Am J Gastroenterol. 2021 Nov 1;116(11):2296-2299. doi: 10.14309/ajg.0000000000001502.
INTRODUCTION
Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown.
METHODS
We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied.
RESULTS
Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery.
DISCUSSION
Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.
简介
外阴受累是克罗恩病（CD）的罕见并发症。外阴 CD 的最佳治疗方法尚不清楚。
方法
我们对 3 个转诊中心的外阴 CD 进行了为期 25 年的回顾性队列研究。研究了临床特征和结局。
结果
共确定了 50 名患者。最常见的外阴症状是疼痛（74%）、肿胀（60%）、溃疡（46%）、结节（36%）和脓肿（34%）。导致症状改善的药物治疗各不相同，有 5 名患者最终需要手术。
讨论
外阴 CD 表现出广泛的症状。尽管有 10%的病例需要手术，但积极的药物治疗通常是有效的。
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