Carta Mauro Giovanni, Cossu Giulia, Pintus Elisa, Zaccheddu Rosanna, Callia Omar, Conti Giuliana, Pintus Mirra, Aviles Gonzalez Cesar Ivan, Massidda Maria Valeria, Mura Gioia, Sardu Claudia, Contu Paolo, Minerba Luigi, Demontis Roberto, Pau Massimiliano, Finco Gabriele, Cocco Eleonora, Penna Maria Pietronilla, Orr Germano, Kalcev Goce, Cabras Federico, Lorrai Stefano, Loviselli Andrea, Velluzzi Fernanda, Monticone Marco, Cacace Enrico, Musu Mario, Rongioletti Franco, Cauli Alberto, Ruggiero Valeria, Scano Alessandra, Crisafulli Antonio, Cosentino Sofia, Atzori Laura, Massa Elena, Mela Quirico, Fortin Dario, Migliaccio Gianmario, Machado Sergio, Romano Ferdinando, Preti Antonio
Dipartimento di Sanità Pubblica, Università degli studi di Cagliari, Cagliari, Italy.
Department of Medical Sciences and Publcic Health, University of Cagliari, Cagliari, Italy.
Clin Pract Epidemiol Ment Health. 2021 Sep 16;17:75-80. doi: 10.2174/1745017902117010075. eCollection 2021.
Physical activity in the elderly is recommended by international guidelines to protect against cognitive decline and functional impairment.
This Randomized Controlled Trial (RCT) was set up to verify whether medium-intensity physical activity in elderly people living in the community is effective in improving cognitive performance.
RCT with parallel and balanced large groups.
Academic university hospital and Olympic gyms.
People aged 65 years old and older of both genders living at home holding a medical certificate for suitability in non-competitive physical activity.
Participants were randomized to a 12-week, 3 sessions per week moderate physical activity program or to a control condition focused on cultural and recreational activities in groups of the same size and timing as the active intervention group. The active phase integrated a mixture of aerobic and anaerobic exercises, including drills of "life movements", strength and balance. The primary outcome was: any change in Addenbrooke's Cognitive Examination Revised (ACE-R) and its subscales.
At the end of the trial, 52 people completed the active intervention, and 53 people completed the control condition. People in the active intervention improved on the ACE-R (ANOVA: F(1;102)=4.32, p=0.040), and also showed better performances on the memory (F(1;102)=5.40 p=0.022) and visual-space skills subscales of the ACE-R (F(1;102)=4.09 p=0.046).
A moderate-intensity exercise administered for a relatively short period of 12 weeks is capable of improving cognitive performance in a sample of elderly people who live independently in their homes.: NCT03858114.
国际指南推荐老年人进行体育活动以预防认知能力下降和功能障碍。
本随机对照试验（RCT）旨在验证社区老年人进行中等强度体育活动是否能有效改善认知表现。
平行且均衡大组的随机对照试验。
学术性大学医院和奥林匹克体育馆。
年龄在65岁及以上、居家生活且持有非竞技体育活动适宜性医学证明的男女。
参与者被随机分配到一个为期12周、每周3次的中等强度体育活动项目组，或分配到一个与积极干预组规模和时间相同的以文化和娱乐活动为重点的对照组。积极阶段综合了有氧和无氧运动，包括“生活动作”训练、力量和平衡训练。主要结局是：修订版Addenbrooke认知检查（ACE-R）及其子量表的任何变化。
试验结束时，52人完成了积极干预，53人完成了对照条件。积极干预组的人在ACE-R上有所改善（方差分析：F(1;102)=4.32，p=0.040），并且在ACE-R的记忆（F(1;102)=5.40，p=0.022）和视觉空间技能子量表上也表现更好（F(1;102)=4.09，p=0.046）。
在相对较短的12周内进行中等强度运动能够改善独立居家生活的老年人群样本的认知表现。试验注册号：NCT03858114。
