Tiruye Getahun, Shiferaw Kassiye, Tura Abera Kenay, Debella Adera, Musa Abdulbasit
School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Department of Obstetrics and Gynaecology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
SAGE Open Med. 2021 Oct 29;9:20503121211053912. doi: 10.1177/20503121211053912. eCollection 2021.
Premature rupture of the membrane is a serious public health problem, especially in low- and middle-income countries with significant maternal and perinatal morbidity and mortality. Despite its substantial contributions to feto-maternal complications, the burden of premature rupture of the membrane was not systematically analyzed in Ethiopia. Hence, this review aimed to identify the burden of premature rupture of the membrane and associated factors among pregnant women in Ethiopia.
PubMed/Medline, Scopus, and African journal online databases and Google Scholar were searched for articles published in the English language. Independent review authors selected and screened studies. Appraisal for methodological quality of studies was conducted using the Joanna Briggs Institute assessment checklist. RevMan 5.3 software was used for meta-analysis. The statistical significance and Egger's test were used to assess heterogeneity and publication bias, respectively.
The pooled prevalence of premature rupture of the membrane among pregnant women in Ethiopia was 9.2% (95% confidence interval = 5.0, 16.4). Factors significantly associated with premature rupture of the membrane were no antenatal care visit (odds ratio = 2.87, confidence interval = 1.34, 6.14), history of premature rupture of the membrane (odds ratio = 4.09, 95% confidence interval = 2.82, 5.91), history of abortion (odds ratio = 3.13, confidence interval = 1.63, 6.01), abnormal vaginal discharge (odds ratio = 6.78, confidence interval = 4.11, 11.16), and urinary tract infection (odds ratio = 3.04, confidence interval = 1.21, 7.63).
Nearly one in ten pregnancies in Ethiopia encounters premature rupture of the membrane complications. The finding highlights improving antenatal care utilization, thus preventing or treating urinary and reproductive tract infections, and tailored interventions for pregnant women with a history of premature rupture of the membrane or abortion contribute to reduced premature rupture of the membrane.
胎膜早破是一个严重的公共卫生问题，尤其在孕产妇和围产期发病率及死亡率较高的低收入和中等收入国家。尽管胎膜早破对母婴并发症有重大影响，但埃塞俄比亚尚未对其负担进行系统分析。因此，本综述旨在确定埃塞俄比亚孕妇中胎膜早破的负担及相关因素。
在PubMed/Medline、Scopus、非洲期刊在线数据库和谷歌学术中检索英文发表的文章。由独立的综述作者选择和筛选研究。使用乔安娜·布里格斯研究所评估清单对研究的方法学质量进行评估。使用RevMan 5.3软件进行荟萃分析。分别使用统计学显著性检验和埃格检验评估异质性和发表偏倚。
埃塞俄比亚孕妇中胎膜早破的合并患病率为9.2%（95%置信区间=5.0，16.4）。与胎膜早破显著相关的因素包括未进行产前检查（比值比=2.87，置信区间=1.34，6.14）、胎膜早破病史（比值比=4.09，95%置信区间=2.82，5.91）、流产史（比值比=3.13，置信区间=1.63，6.01）、异常阴道分泌物（比值比=6.78，置信区间=4.11，11.16）和尿路感染（比值比=3.04，置信区间=1.21，7.63）。
埃塞俄比亚近十分之一的妊娠会出现胎膜早破并发症。这一发现凸显了提高产前检查利用率的重要性，从而预防或治疗泌尿生殖道感染，针对有胎膜早破或流产史的孕妇采取针对性干预措施有助于降低胎膜早破的发生率。
