Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Section on Growth and Obesity, Division of Intramural Research, Department of Health and Human Services, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Obesity (Silver Spring). 2021 Nov;29(11):1760-1769. doi: 10.1002/oby.23281.
Beyond sleep duration, other facets of sleep such as variability and timing may be associated with obesity risk in youth. However, data are limited. Using a longitudinal design, this study tested whether multiple facets of sleep were associated with fat mass gain over 1 year.
A convenience sample of non-treatment-seeking youth (age 8-17 years) wore actigraphy monitors for 14 days. Average weekly sleep duration, within-person sleep duration variability, weekend catch-up sleep, bedtime and wake time shift, social jet lag, bedtime, wake time, and sleep midpoint were calculated. The association of each facet of baseline sleep with 1-year fat mass, adjusting for baseline fat mass and height, was examined.
A total of 137 youths (54.0% female; mean [SD], age 12.5 [2.6] years; 28.4% non-Hispanic Black or African American; baseline fat mass = 15.3 [8.9] kg; 1-year fat mass = 17.0 [10.0] kg; 28.5% with baseline overweight or obesity) were studied. Wake time (p = 0.03) and sleep midpoint (p = 0.02) were inversely associated with 1-year fat mass, such that earlier wake time and midpoint were associated with higher 1-year fat mass. No other facet of sleep was significantly associated with 1-year fat mass (p > 0.09).
Using objective measures, youth with earlier wake times and sleep midpoints had greater gains in fat mass. Additional research is needed to determine whether sleep timing may be a modifiable target to prevent pediatric obesity.
除了睡眠时间之外，睡眠的其他方面，如变异性和时间安排，也可能与青少年肥胖风险相关。然而，相关数据有限。本研究采用纵向设计，检验了睡眠的多个方面是否与 1 年内体脂肪增加有关。
采用便利抽样法，选择非治疗性寻求的青少年（8-17 岁）佩戴活动记录仪 14 天。计算平均每周睡眠时间、个体内睡眠持续时间变异性、周末补觉、就寝时间和醒来时间变化、社交时差、就寝时间、醒来时间和睡眠中点。检验基线睡眠各个方面与 1 年体脂肪的相关性，调整基线体脂肪和身高。
共纳入 137 名青少年（54.0%为女性；平均[标准差]年龄 12.5[2.6]岁；28.4%为非西班牙裔黑种人或非裔美国人；基线体脂肪=15.3[8.9]kg；1 年体脂肪=17.0[10.0]kg；28.5%基线超重或肥胖）。发现醒来时间（p=0.03）和睡眠中点（p=0.02）与 1 年体脂肪呈负相关，即醒来时间和中点越早，1 年体脂肪增加越多。睡眠的其他方面与 1 年体脂肪无显著相关性（p>0.09）。
使用客观指标发现，醒来时间和睡眠中点较早的青少年体脂肪增加更多。需要进一步研究以确定睡眠时间是否可以作为预防儿童肥胖的可改变目标。
