Aier School of Ophthalmology, Central South University, Changsha, China.
Aier Eye Hospital Group, Changsha, China.
Transl Vis Sci Technol. 2023 Oct 3;12(10):8. doi: 10.1167/tvst.12.10.8.
The purpose of this study was to explore two-dimensional peripheral refraction and higher-order aberrations (HOAs) induced by orthokeratology lens decentration.
Two-dimensional peripheral refraction and HOAs in a rectangular field (horizontally 60 degrees and vertically 36 degrees) were obtained using an open-view Hartmann-Shack wavefront sensor. The peripheral field was divided into 8 regions according to a combination of superior (UZ) or inferior (LZ) and a value, 1 (T25 to T30), 2 (T20 to T25), 3 (N20 to N25), or 4 (N25 to N30). The decentration of the lens was evaluated based on the change of power in the front of the tangential corneal map. All measurements were taken at the baseline and 1 month after lens fitting.
In total, 134 myopic children (age = 12.47 ± 1.70 years, SER = -2.44 ± 1.10 diopters [D]) were recruited. In general, horizontally asymmetrical change was observed in relative peripheral refraction (RPR), spherical aberration (SA), and horizontal coma. The root-mean square of higher order aberration (RMSHOA) and vertical coma demonstrated radial symmetrical change and vertically asymmetric change, respectively. Relative peripheral myopia was significantly increased after the treatment, with more myopic refraction in the temporal side. RPR changes in UZ2, UZ3, UZ4, LZ1, and LZ2 were related to the amount of lens decentration (r ≈ 0.4, P < 0.05). All HOAs increased after lens fitting (around 0.03 um, 0.02 um, 0.04 um, and 0.41 um for SA, horizontal COMA, vertical COMA, and RMSHOA in the periphery region).
RPR and HOAs are related to lens decentration, which might contribute to the efficacy of orthokeratology.
The study found a decentration-related optical feature after 1 month of lens wear, which is a suggested protective factor in myopia treatment. The findings might provide new insights for customized contact lens myopia treatment based on optics.
本研究旨在探讨角膜塑形术镜片离焦引起的二维周边屈光度和高阶像差（HOA）。
采用开放式视野哈特曼-夏克波前传感器获得矩形视野（水平 60 度，垂直 36 度）的二维周边屈光度和 HOA。根据上（UZ）或下（LZ）和值 1（T25 至 T30）、2（T20 至 T25）、3（N20 至 N25）或 4（N25 至 N30）的组合，将周边视野分为 8 个区域。镜片的偏心度根据角膜切线图前部功率的变化来评估。所有测量均在基线和配镜后 1 个月进行。
共纳入 134 名近视儿童（年龄=12.47±1.70 岁，等效球镜度[SER]=-2.44±1.10 屈光度[D]）。总体上，水平方向观察到相对周边屈光度（RPR）、球差（SA）和水平彗差的非对称变化。高阶像差均方根（RMSHOA）和垂直彗差分别呈现径向对称和垂直非对称变化。治疗后相对周边近视明显增加，颞侧近视程度更高。UZ2、UZ3、UZ4、LZ1 和 LZ2 的 RPR 变化与镜片偏心量有关（r≈0.4，P<0.05）。配镜后所有 HOA 均增加（SA、水平彗差、垂直彗差和周边区域 RMSHOA 分别增加约 0.03μm、0.02μm、0.04μm 和 0.41μm）。
RPR 和 HOA 与镜片偏心度有关，这可能是角膜塑形术疗效的原因之一。
温晓平
