National Center for Soybean Improvement, State Key Laboratory of Crop Genetics and Germplasm Enhancement, Nanjing Agricultural University, Nanjing, China.
Crop Improvement Division, ICAR- Indian Institute of Pulses Research (ICAR- IIPR), Kanpur, India.
Commun Biol. 2021 Nov 4;4(1):1266. doi: 10.1038/s42003-021-02782-y.
Climate change with altered pest-disease dynamics and rising abiotic stresses threatens resource-constrained agricultural production systems worldwide. Genomics-assisted breeding (GAB) approaches have greatly contributed to enhancing crop breeding efficiency and delivering better varieties. Fast-growing capacity and affordability of DNA sequencing has motivated large-scale germplasm sequencing projects, thus opening exciting avenues for mining haplotypes for breeding applications. This review article highlights ways to mine haplotypes and apply them for complex trait dissection and in GAB approaches including haplotype-GWAS, haplotype-based breeding, haplotype-assisted genomic selection. Improvement strategies that efficiently deploy superior haplotypes to hasten breeding progress will be key to safeguarding global food security.
气候变化改变了病虫害动态和非生物胁迫的发生频率，这对资源有限的全球农业生产系统构成了威胁。基因组辅助育种（GAB）方法极大地促进了作物育种效率的提高，并带来了更好的品种。DNA 测序的快速增长能力和可负担性促使大规模的种质资源测序项目得以开展，从而为挖掘用于育种应用的单倍型开辟了令人兴奋的途径。本文综述了挖掘单倍型并将其应用于复杂性状解析和 GAB 方法的途径，包括单倍型-GWAS、基于单倍型的育种和单倍型辅助基因组选择。高效利用优势单倍型加速育种进程的改进策略将是保障全球粮食安全的关键。
