Carini Francesco, Gagliardo Carola, Scaglione Marco, Giammanco Marco, Tomasello Giovanni
Università degli Studi di Palermo.
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Acta Biomed. 2021 Nov 3;92(5):e2021264. doi: 10.23750/abm.v92i5.11100.
inflammatory bowel diseases (IBD) are chronic disorders that affect the gastrointestinal tract but which also present extraintestinal manifestations. One of the problems related to IBD is the presence of both female and male infertility.
determine the correlation between IBD and male and female infertility by analyzing the literature.
Studies carried out in the last twenty years have been selected through the pubmed search engine. Only studies were selected that in their conclusions showed a real correlation between IBD and infertility.
the first cause of infertility in both sexes is related to the surgical interventions that patients have to face during the course of the disease, but there are also psychological causes or causes related to the use of drugs used for therapy.
further studies are needed to understand what are the real mechanisms underlying infertility in subjects suffering from IBD.
炎症性肠病（IBD）是一种影响胃肠道的慢性疾病，但也会出现肠外表现。与IBD相关的问题之一是男性和女性不育症的存在。
通过分析文献确定IBD与男性和女性不育症之间的相关性。
通过PubMed搜索引擎筛选过去二十年进行的研究。仅选择那些在结论中显示IBD与不育症之间存在真实相关性的研究。
两性不育的首要原因与患者在疾病过程中必须面对的手术干预有关，但也有心理原因或与治疗所用药物相关的原因。
需要进一步研究以了解IBD患者不育的真正潜在机制。
