Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, 110085, India.
Amity Institute of Biotechnology, Noida, Uttar Pradesh, 201313, India.
Cell Tissue Bank. 2022 Dec;23(4):939-947. doi: 10.1007/s10561-021-09971-3. Epub 2021 Nov 5.
A Biobank/Biorepository is an organized collection of resources that can be accessed to retrieve biological material and data for research purpose. Human specimen repositories (adult and paediatric) take lead amongst the various types of biorepositories. Patient's bio samples are a rich source of genetic information and therefore can form the basis of diagnostics, forensics and multidimensional disciplines of biomedical research. The advent of molecular techniques and the technological upsurge in the management of genetic resources has facilitated the human DNA sampling and data collection leading to the emergence of DNA banking. DNA banking has paved a new path in precision oncology and personalized medicine. This article highlights the current scenario concerning the general awareness, scientific consciousness and current national and international practices being initiated and in practice for the establishment of bio banking facilities particularly DNA bio banking.
生物银行/生物库是一种有组织的资源集合,可以获取生物材料和数据用于研究目的。人类标本库(成人和儿科)在各种类型的生物库中处于领先地位。患者的生物样本是丰富的遗传信息来源,因此可以成为诊断、法医学和多维生物医学研究领域的基础。分子技术的出现和遗传资源管理的技术飞跃促进了人类 DNA 采样和数据收集,从而导致 DNA 银行的出现。DNA 银行业为精准肿瘤学和个性化医学开辟了新途径。本文重点介绍了目前在建立生物银行设施(特别是 DNA 生物银行)方面的一般认识、科学意识以及国家和国际上正在发起和实践的情况。