Department of Bacteriology, Animal and Plant Health Agency, Weybridge, New Haw, Addlestone, Surrey, KT15 3NB, UK.
Centre for Zoonoses and Environmental Microbiology - Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), 3720 BA, Bilthoven, The Netherlands.
Curr Opin Microbiol. 2021 Dec;64:152-158. doi: 10.1016/j.mib.2021.09.011. Epub 2021 Oct 29.
To understand the dynamics of antimicrobial resistance (AMR), in a One-Health perspective, surveillance play an important role. Monitoring systems already exist in the human health and livestock sectors, but there are no environmental monitoring programs. Therefore there is an urgent need to initiate environmental AMR monitoring programs nationally and globally, which will complement existing systems in different sectors. However, environmental programs should not only identify anthropogenic influences and levels of AMR, but they should also allow for identification of transmissions to and from human and animal populations. In the current review we therefore propose using antimicrobial resistant Escherichia coli as indicators for monitoring occurrence and levels of AMR in the environment, including wildlife.
为了从“同一健康”角度理解抗生素耐药性（AMR）的动态，监测发挥着重要作用。在人类健康和畜牧业领域已经存在监测系统，但不存在环境监测方案。因此，迫切需要在国家和全球范围内启动环境抗生素耐药性监测方案，以补充不同部门现有的系统。然而，环境方案不仅应查明人为影响和抗生素耐药性水平，还应查明向人类和动物群体以及来自这些群体的传播情况。因此，在目前的审查中，我们建议使用耐抗生素的大肠杆菌作为指标，以监测环境（包括野生动物）中抗生素耐药性的发生和水平。
