Leonard Anne Fc, Morris Dearbháile, Schmitt Heike, Gaze William H
University of Exeter Medical School, Environment and Sustainability Institute, University of Exeter, Cornwall TR10 9FE, UK.
Antimicrobial Resistance and Microbial Ecology Group, School of Medicine, National University of Ireland Galway, Ireland.
Curr Opin Microbiol. 2022 Feb;65:40-46. doi: 10.1016/j.mib.2021.10.004. Epub 2021 Oct 29.
Antimicrobial resistance (AMR) is widely recognised as a considerable threat to human health, wellbeing and prosperity. Many clinically important antibiotic resistance genes are understood to have originated in the natural environment. However, the complex interactions between humans, animals and the environment makes the health implications of environmental AMR difficult to quantify. This narrative review focuses on the current state of knowledge regarding antibiotic resistant bacteria (ARB) in natural bathing waters and implications for human health. It considers the latest research focusing on the transmission of ARB from bathing waters to humans. The limitations of existing evidence are discussed, as well as research priorities. The authors are of the opinion that future studies should include faecally contaminated bathing waters and people exposed to these environments to accurately parameterise environment-to-human transmission.
抗菌药物耐药性（AMR）被广泛认为是对人类健康、福祉和繁荣的重大威胁。许多临床上重要的抗生素耐药基因被认为起源于自然环境。然而，人类、动物和环境之间的复杂相互作用使得环境AMR对健康的影响难以量化。本叙述性综述聚焦于天然浴场水中抗生素耐药菌（ARB）的现有知识状况及其对人类健康的影响。它考虑了聚焦于ARB从浴场水传播至人类的最新研究。讨论了现有证据的局限性以及研究重点。作者认为，未来的研究应纳入受粪便污染的浴场水以及接触这些环境的人群，以准确确定从环境到人类的传播参数。
