Kelly Katherine A, Patel Pious D, Salwi Sanjana, Iii Harold N Lovvorn, Naftel Robert
1Vanderbilt University School of Medicine, Nashville.
2Department of Pediatric Surgery, Vanderbilt University Medical Center, Nashville; and.
J Neurosurg Pediatr. 2021 Nov 5;29(3):335-341. doi: 10.3171/2021.7.PEDS20820. Print 2022 Mar 1.
Low socioeconomic status is a determinant of pediatric traumatic brain injury (TBI) incidence and severity. In this study, the authors used National (Nationwide) Inpatient Sample (NIS) data to evaluate socioeconomic and health disparities among children hospitalized after TBI.
This retrospective study identified pediatric patients aged 0 to 19 years with ICD-9 codes for TBI in the NIS database from 2012 to 2015. Socioeconomic variables included race, sex, age, census region, and median income of the patient residential zip code. Outcomes included mechanism of injury, hospital length of stay (LOS), cost, disposition at discharge, death, and inpatient complications. Multivariate linear regressions in log scale were built for LOS and cost. Logistic regressions were built for death, disposition, and inpatient complications.
African American, Hispanic, and Native American patients experienced longer LOSs (β 0.06, p < 0.001; β 0.03, p = 0.03; β 0.13, p = 0.02, respectively) and increased inpatient costs (β 0.13, p < 0.001; β 0.09, p < 0.001; β 0.14, p = 0.03, respectively). Females showed increased rates of medical complications (OR 1.57, p < 0.001), LOS (β 0.025, p = 0.02), and inpatient costs (p = 0.04). Children aged 15 to 19 years were less likely to be discharged home (OR 3.99, p < 0.001), had increased mortality (OR 1.32, p = 0.03) and medical complications (OR 1.84, p < 0.001), and generated increased costs (p < 0.001).
The study results have demonstrated that racial minorities, females, older children, and children in lower socioeconomic groups were at increased risk of poor outcomes following TBI, including increased LOS, medical complications, mortality, inpatient costs, and worse hospital disposition. Public education and targeted funding for these groups will ensure that all children have equal opportunity for optimal clinical outcomes following TBI.
社会经济地位低下是儿童创伤性脑损伤(TBI)发生率和严重程度的一个决定因素。在本研究中,作者使用国家(全国)住院患者样本(NIS)数据来评估TBI后住院儿童的社会经济和健康差异。
这项回顾性研究在2012年至2015年的NIS数据库中识别出年龄在0至19岁、具有TBI的ICD - 9编码的儿科患者。社会经济变量包括种族、性别、年龄、人口普查区域以及患者居住邮政编码区的收入中位数。结局包括损伤机制、住院时间(LOS)、费用、出院处置、死亡和住院并发症。针对LOS和费用建立对数尺度的多变量线性回归。针对死亡、处置和住院并发症建立逻辑回归。
非裔美国人、西班牙裔和美国原住民患者的住院时间更长(分别为β 0.06,p < 0.001;β 0.03,p = 0.03;β 0.13,p = 0.02)且住院费用增加(分别为β 0.13,p < 0.001;β 0.09,p < 0.001;β 0.14,p = 0.03)。女性的医疗并发症发生率增加(OR 1.57,p < 0.001)、住院时间(β 0.025,p = 0.02)和住院费用(p = 0.04)增加。15至19岁的儿童出院回家的可能性较小(OR 3.99,p < 0.001),死亡率增加(OR 1.32,p = 0.03)和医疗并发症增加(OR 1.84,p < 0.001),且费用增加(p < 0.001)。
研究结果表明,少数族裔、女性、年龄较大的儿童以及社会经济地位较低群体中的儿童在TBI后出现不良结局的风险增加,包括住院时间延长、医疗并发症、死亡率、住院费用以及更差的出院处置情况。针对这些群体的公共教育和定向资金投入将确保所有儿童在TBI后有平等机会获得最佳临床结局。