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非典型食管颗粒细胞瘤:病例报告

Atypical esophageal granular cell tumor: Case report.

作者信息

Benchekroun Zineb, Akammar Amal, Bennani Hajar, Haloua Meriem, Lamrani Youssef Alaoui, Boubbou Meriem, Chbani Leila, Maâroufi Mustapha, Alami Badreddine

机构信息

Department of radiology, CHU HASSAN II FES, Morocco.

Anatomic pathology department of CHU HASSAN II of FEZ, Morocco.

出版信息

Radiol Case Rep. 2021 Oct 22;16(12):3995-3999. doi: 10.1016/j.radcr.2021.09.040. eCollection 2021 Dec.

DOI:10.1016/j.radcr.2021.09.040
PMID:34745406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8555436/
Abstract

Esophageal granular cell tumors (GCTs), or also called Abrikossoff's tumor are rare benign tumors originating from Schwann cells most commonly found in the skin, subcutaneous tissue, and tongue. Approximately 5% -8% arise in the gastrointestinal tract, and one-third of these tumors arise in the esophagus [1]. This neoplasm has a benign behavior usually, but there have been described a malignant transformation in 2% -3% of the cases. Herein, we discuss a case of a 70-year-old male patient with no pathological background, admitted for dysphagia evolving in 3 months that was explored with endoscopy and CT, the diagnosis at this level was challenging but the histopathology and Immunohistochemistry confirmed the presence of granular cells thus confirm the diagnosis. The purpose of our work is to report the uncommon evolution of an Abrikossoff 's tumor located in the esophagus, as a warning of the possible malignant transformation of this tumor mostly benign; also we made a review of the literature.

摘要

食管颗粒细胞瘤(GCTs),也称为阿布里科索夫瘤,是一种罕见的良性肿瘤,起源于施万细胞,最常见于皮肤、皮下组织和舌部。约5% - 8%发生于胃肠道,其中三分之一的肿瘤发生于食管[1]。这种肿瘤通常具有良性行为,但已有2% - 3%的病例发生恶变的报道。在此,我们讨论一例70岁男性患者,无病理背景,因3个月内逐渐出现吞咽困难入院,接受了内镜检查和CT检查,当时的诊断具有挑战性,但组织病理学和免疫组织化学证实存在颗粒细胞,从而确诊。我们工作的目的是报告位于食管的阿布里科索夫瘤的罕见演变情况,以警示这种大多为良性的肿瘤可能发生恶变;我们还对文献进行了回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/8c9192cc398b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/7ee8e66ebdde/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/838f1495ebc3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/e8a83dafe5f7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/8c9192cc398b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/7ee8e66ebdde/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/838f1495ebc3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/e8a83dafe5f7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c51/8555436/8c9192cc398b/gr4.jpg

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Esophageal granular cell tumors: Case report and literature review.食管颗粒细胞瘤:病例报告与文献综述
World J Gastrointest Oncol. 2015 Aug 15;7(8):123-7. doi: 10.4251/wjgo.v7.i8.123.
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Granular cell tumor of the esophagus: a clinicopathological study of 31 cases.食管颗粒细胞瘤:31例临床病理研究
Int J Clin Exp Pathol. 2014 Jun 15;7(7):4000-7. eCollection 2014.
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Granular cell tumor of the cervical esophagus: case report and literature review of an unusual cause of Dysphagia.颈段食管颗粒细胞瘤:吞咽困难罕见病因的病例报告及文献综述
Head Neck Pathol. 2013 Sep;7(3):274-9. doi: 10.1007/s12105-012-0408-x. Epub 2012 Nov 11.
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Giant fibrovascular polyp of the esophagus-imaging techniques for proper treatment planning: report of two cases.食管巨大纤维血管性息肉——用于合理治疗规划的成像技术:两例报告
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Turk J Gastroenterol. 2008 Sep;19(3):184-8.
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Turk J Gastroenterol. 2007 Sep;18(3):188-91.
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Dis Esophagus. 2007;20(5):436-43. doi: 10.1111/j.1442-2050.2007.00692.x.
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