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建立一个基于SEIR的框架,用于对COVID-19感染、住院和死亡情况进行本地建模。

Establishing an SEIR-based framework for local modelling of COVID-19 infections, hospitalisations and deaths.

作者信息

Wood R M, Pratt A C, Murch B J, Powell A L, Booton R D, Thomas D G, Twigger J, Diakou E, Coleborn S, Manning T, Davies C, Turner K M

机构信息

Bristol, North Somerset and South Gloucestershire CCG, National Health Service, Bristol, UK.

School of Management, University of Bath, Bath, UK.

出版信息

Health Syst (Basingstoke). 2021 Sep 6;10(4):337-347. doi: 10.1080/20476965.2021.1973348. eCollection 2021.

DOI:10.1080/20476965.2021.1973348
PMID:34745593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8567954/
Abstract

Without timely assessments of the number of COVID-19 cases requiring hospitalisation, healthcare providers will struggle to ensure an appropriate number of beds are made available. Too few could cause excess deaths while too many could result in additional waits for elective treatment. As well as supporting capacity considerations, reliably projecting future "waves" is important to inform the nature, timing and magnitude of any localised restrictions to reduce transmission. In making the case for locally owned and locally configurable models, this paper details the approach taken by one major healthcare system in founding a multi-disciplinary "Scenario Review Working Group", comprising commissioners, public health officials and academic epidemiologists. The role of this group, which met weekly during the pandemic, was to define and maintain an evolving library of plausible scenarios to underpin projections obtained through an SEIR-based compartmental model. Outputs have informed decision-making at the system's major incident Bronze, Silver and Gold Commands. This paper presents illustrated examples of use and offers practical considerations for other healthcare systems that may benefit from such a framework.

摘要

如果不及时评估需要住院治疗的新冠肺炎病例数量,医疗服务提供者将难以确保提供足够数量的床位。床位过少可能导致额外死亡,而床位过多则可能导致择期治疗的等待时间延长。除了支持容量考量外,可靠地预测未来的“疫情波”对于确定任何局部限制措施的性质、时间和规模以减少传播至关重要。在论证本地拥有和本地可配置模型时,本文详细介绍了一个主要医疗系统在组建一个多学科“情景审查工作组”时所采取的方法,该工作组由专员、公共卫生官员和学术流行病学家组成。该小组在疫情期间每周开会,其作用是定义并维护一个不断演变的合理情景库,以支持通过基于易感-暴露-感染-康复(SEIR)的分区模型获得的预测。其产出为该系统的重大事件青铜、白银和黄金指挥部的决策提供了依据。本文展示了使用示例,并为其他可能受益于此类框架的医疗系统提供了实际考量。

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本文引用的文献

1
Sensitivity to model structure: a comparison of compartmental models in epidemiology.对模型结构的敏感性:流行病学中房室模型的比较
Health Syst (Basingstoke). 2016;5(3):178-191. doi: 10.1057/hs.2015.2. Epub 2017 Dec 19.
2
Predicting and forecasting the impact of local outbreaks of COVID-19: use of SEIR-D quantitative epidemiological modelling for healthcare demand and capacity.预测和预报 COVID-19 局部暴发的影响:使用 SEIR-D 定量流行病学模型预测医疗需求和能力。
Int J Epidemiol. 2021 Aug 30;50(4):1103-1113. doi: 10.1093/ije/dyab106.
3
Real-time nowcasting and forecasting of COVID-19 dynamics in England: the first wave.英格兰 COVID-19 动力学的实时即时预报和预测:第一波疫情。
Philos Trans R Soc Lond B Biol Sci. 2021 Jul 19;376(1829):20200279. doi: 10.1098/rstb.2020.0279. Epub 2021 May 31.
4
The Value of Triage during Periods of Intense COVID-19 Demand: Simulation Modeling Study.高强度 COVID-19 需求时期的分诊价值:模拟建模研究。
Med Decis Making. 2021 May;41(4):393-407. doi: 10.1177/0272989X21994035. Epub 2021 Feb 9.
5
Estimating the COVID-19 epidemic trajectory and hospital capacity requirements in South West England: a mathematical modelling framework.估算英格兰西南部 COVID-19 疫情轨迹和医院容量需求:数学建模框架。
BMJ Open. 2021 Jan 7;11(1):e041536. doi: 10.1136/bmjopen-2020-041536.
6
Nosocomial SARS-CoV-2 transmission in postoperative infection and mortality: analysis of 14 798 procedures.术后感染和死亡率中的医院获得性 SARS-CoV-2 传播:14798 例手术分析。
Br J Surg. 2020 Dec;107(13):1708-1712. doi: 10.1002/bjs.12053. Epub 2020 Oct 8.
7
Covid-19: Waiting times in England reach record highs.新冠疫情:英国的候诊时间创下历史新高。
BMJ. 2020 Sep 11;370:m3557. doi: 10.1136/bmj.m3557.
8
Managing uncertainty in the covid-19 era.应对新冠疫情时代的不确定性。
BMJ. 2020 Sep 1;370:m3349. doi: 10.1136/bmj.m3349.
9
Predicting the second wave of COVID-19 in Washtenaw County, MI.预测密歇根州 Washtenaw 县的第二波 COVID-19 疫情。
J Theor Biol. 2020 Dec 21;507:110461. doi: 10.1016/j.jtbi.2020.110461. Epub 2020 Aug 29.
10
Misconceptions about weather and seasonality must not misguide COVID-19 response.关于天气和季节性的误解绝不能误导对新冠疫情的应对。
Nat Commun. 2020 Aug 27;11(1):4312. doi: 10.1038/s41467-020-18150-z.