2019冠状病毒病感染中与皮质类固醇治疗相关的鼻窦眼眶毛霉菌病
Sinoorbital Mucormycosis Associated with Corticosteroid Therapy in COVID-19 Infection.
作者信息
Mehrabi Zeinab, Salimi Maryam, Niknam Kianoush, Mohammadi Farzaneh, Mamaghani Hesan Jelodari, Sasani Mohammad Reza, Ashraf Mohammad Javad, Salimi Amirhossein, Zahedroozegar Mohammad Hassan, Erfani Zohreh
机构信息
Department of Internal Medicine, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Case Rep Ophthalmol Med. 2021 Oct 28;2021:9745701. doi: 10.1155/2021/9745701. eCollection 2021.
BACKGROUND
Mucormycosis is a rare and invasive fungal infection, affecting almost exclusively immunocompromised individuals. Immunosuppressive effects of corticosteroids which are widely prescribed in COVID-19 patients might be a predisposing factor for opportunistic infections even though the other factors should also be considered. . A middle-aged man without any significant past medical history was admitted to the hospital due to a severe COVID-19 infection. He received a high dose of corticosteroids as a part of the treatment. Five days after discharge, he presents with a headache and fever. Eventually, orbital mucormycosis was diagnosed for him and he was treated with antifungal medications.
CONCLUSION
Opportunistic infections should be considered during the current pandemic of COVID-19, during which corticosteroids are widely prescribed.
背景
毛霉病是一种罕见的侵袭性真菌感染，几乎仅影响免疫功能低下的个体。尽管还应考虑其他因素，但在新冠病毒病（COVID-19）患者中广泛使用的皮质类固醇的免疫抑制作用可能是机会性感染的一个诱发因素。一名无重大既往病史的中年男子因严重的COVID-19感染入院。作为治疗的一部分，他接受了高剂量的皮质类固醇治疗。出院五天后，他出现头痛和发热。最终，他被诊断为眼眶毛霉病，并接受了抗真菌药物治疗。
结论
在当前COVID-19大流行期间，当皮质类固醇被广泛使用时，应考虑机会性感染。
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