Giralico Leah C, Makii Rebecca, Pray Betsy A, Parker Valerie J
Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, USA.
Department of Veterinary Biosciences, The Ohio State University College of Veterinary Medicine, USA.
Case Rep Vet Med. 2021 Oct 29;2021:6622767. doi: 10.1155/2021/6622767. eCollection 2021.
A 9-year-old male intact mixed-breed dog was presented to The Ohio State University Veterinary Medical Center for evaluation of two days' duration of weakness, lethargy, inappetence, and one episode of vomiting the day of presentation. On presentation, the dog was depressed and tetraparetic. He was noted to be icteric and dehydrated. Obesity and truncal alopecia with a "rat tail" appearance were observed. Diagnostic testing revealed evidence of an acute hepatopathy and peritonitis. Given the dog's neurologic status, physical examination abnormalities, including a "tragic facial expression", and hyperlipidemia, there was concern for possible myxedema coma. A thyroid panel was consistent with hypothyroidism. The dog experienced respiratory arrest prior to initiation of therapy, and an autopsy confirmed the presence of subacute necrotizing cholangiohepatitis, marked atherosclerosis, and severe thyroid atrophy. These clinical and pathologic changes were supportive of myxedema coma.
一只9岁未绝育的混血雄性犬被送至俄亥俄州立大学兽医学院进行评估，该犬出现了为期两天的虚弱、嗜睡、食欲不振症状，并在就诊当天有一次呕吐。就诊时，该犬精神沉郁且四肢轻瘫。发现其黄疸且脱水。观察到肥胖及躯干脱毛呈“鼠尾”外观。诊断性检查显示有急性肝病和腹膜炎的证据。鉴于该犬的神经状态、体格检查异常（包括“悲剧性面部表情”）及高脂血症，怀疑可能为黏液性水肿昏迷。甲状腺功能检查结果符合甲状腺功能减退。该犬在开始治疗前发生呼吸骤停，尸检证实存在亚急性坏死性胆管肝炎、明显的动脉粥样硬化和严重的甲状腺萎缩。这些临床和病理变化支持黏液性水肿昏迷的诊断。
