Matsuno Osamu, Minamoto Seijiro
Department of Medicine for Allergic Disease, Osaka Habikino Medical Center, 3-7-1 Habikino, Habikino City, Osaka, 583-8588, Japan.
Respir Med Case Rep. 2021 Oct 21;34:101539. doi: 10.1016/j.rmcr.2021.101539. eCollection 2021.
Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by excessive eosinophil accumulation in the peripheral blood and affected tissues with development of granulomatous vasculitic organ damage. Although upper airway and neck involvement is seen in patients with EGPA, retropharyngeal inflammation has never been reported. We report a case of retropharyngeal edema in a 70-year-old woman with EGPA. Her symptoms improved and the retropharyngeal edema disappeared on computed tomography following treatment. EGPA should be considered as a differential diagnosis in patients with asthma presenting with neck swelling and dysphagia.
嗜酸性肉芽肿性多血管炎（EGPA）的特征是外周血和受累组织中嗜酸性粒细胞过度积聚，并伴有肉芽肿性血管炎性器官损伤。虽然EGPA患者可见上呼吸道和颈部受累，但咽后炎症从未有过报道。我们报告一例70岁患有EGPA的女性出现咽后水肿的病例。治疗后，她的症状有所改善，计算机断层扫描显示咽后水肿消失。对于出现颈部肿胀和吞咽困难的哮喘患者，应考虑将EGPA作为鉴别诊断。
